4-Desmethoxy Omeprazole
Based on 1 Customer Validation
4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 110374-16-8
- Formula: C16H17N3O2S
- Molecular Weight:315.39
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 110374-16-8
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Appearance Powder
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Molecular Weight 315.39
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Formula C16H17N3O2S
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Color white
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SMILES
COC1=CC=C2N=C(S(CC3=NC=C(C)C=C3C)=O)NC2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (396.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
[1]. Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7. [Content Brief]
[2]. Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37(1):145-50. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1707 mL | 15.8534 mL | 31.7068 mL | 79.2669 mL |
| 5 mM | 0.6341 mL | 3.1707 mL | 6.3414 mL | 15.8534 mL | |
| 10 mM | 0.3171 mL | 1.5853 mL | 3.1707 mL | 7.9267 mL | |
| 15 mM | 0.2114 mL | 1.0569 mL | 2.1138 mL | 5.2845 mL | |
| 20 mM | 0.1585 mL | 0.7927 mL | 1.5853 mL | 3.9633 mL | |
| 25 mM | 0.1268 mL | 0.6341 mL | 1.2683 mL | 3.1707 mL | |
| 30 mM | 0.1057 mL | 0.5284 mL | 1.0569 mL | 2.6422 mL | |
| 40 mM | 0.0793 mL | 0.3963 mL | 0.7927 mL | 1.9817 mL | |
| 50 mM | 0.0634 mL | 0.3171 mL | 0.6341 mL | 1.5853 mL | |
| 60 mM | 0.0528 mL | 0.2642 mL | 0.5284 mL | 1.3211 mL | |
| 80 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9908 mL | |
| 100 mM | 0.0317 mL | 0.1585 mL | 0.3171 mL | 0.7927 mL |
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