4-Desmethoxy Omeprazole
Based on 1 Customer Validation
4-Desmethoxy Omeprazole is a metabolite of Omeprazole (HY-B0113) and an impurity in its preparation process. Omeprazole is an orally active H+,K+-ATPase inhibitor and also a proton pump inhibitor. Omeprazole competitively inhibits the activity of CYP2C19, CYP3A4, and CYP2C9. Omeprazole inhibits gastric acid secretion and can be used for the treatment of acid-related gastrointestinal disorders. Omeprazole also has neuroprotective and antibacterial effects.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.99%
- CAS. Nr.: 110374-16-8
- Formel: C16H17N3O2S
- Molecular Weight:315.39
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-135111R
4-Desmethoxy Omeprazole (Standard)Reference Standard -
HY-G0007
Omeprazole sulfoneUlcer Healing Supporter -
HY-G0006
Omeprazole sulfideOmeprazole Metabolite -
HY-17023
Esomeprazole sodiumProton Pump Inhibitor -
HY-G0006R
Omeprazole sulfide (Standard) -
HY-G0007R
Omeprazole sulfone (Standard) -
HY-17023R
Esomeprazole sodium (Standard)Proton Pump Inhibitor
Biologische Aktivität
Beschreibung
In Vitro
4-Desmethoxy Omeprazole can serve as a reference substance for the quality control and impurity identification of Omeprazole[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 110374-16-8
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Appearance Powder
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Molecular Weight 315.39
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Formel C16H17N3O2S
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Color white
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SMILES
COC1=CC=C2N=C(S(CC3=NC=C(C)C=C3C)=O)NC2=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 125 mg/mL (396.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Protokoll
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1707 mL | 15.8534 mL | 31.7068 mL | 79.2669 mL |
| 5 mM | 0.6341 mL | 3.1707 mL | 6.3414 mL | 15.8534 mL | |
| 10 mM | 0.3171 mL | 1.5853 mL | 3.1707 mL | 7.9267 mL | |
| 15 mM | 0.2114 mL | 1.0569 mL | 2.1138 mL | 5.2845 mL | |
| 20 mM | 0.1585 mL | 0.7927 mL | 1.5853 mL | 3.9633 mL | |
| 25 mM | 0.1268 mL | 0.6341 mL | 1.2683 mL | 3.1707 mL | |
| 30 mM | 0.1057 mL | 0.5284 mL | 1.0569 mL | 2.6422 mL | |
| 40 mM | 0.0793 mL | 0.3963 mL | 0.7927 mL | 1.9817 mL | |
| 50 mM | 0.0634 mL | 0.3171 mL | 0.6341 mL | 1.5853 mL | |
| 60 mM | 0.0528 mL | 0.2642 mL | 0.5284 mL | 1.3211 mL | |
| 80 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9908 mL | |
| 100 mM | 0.0317 mL | 0.1585 mL | 0.3171 mL | 0.7927 mL |
4-Desmethoxy Omeprazole Related Classifications
HY-135111 Related Classifications
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Keywords
- 4-Desmethoxy Omeprazole
- 110374-16-8
- Drug Metabolite
- Drug Intermediate
- accurate mass
- omeprazole metabolite
- retention times
- fragment ion analysis
- 4-desmethoxy omeprazole
- UHPLC-QTOF-MS
- 4-hydroxy-omeprazole sulphide
- internet-obtained omeprazole formulations
- internet-sourced omeprazole samples
- effluent wastewater
- Inhibitor
- inhibitor
- inhibit