4-sec-Butylphenol
4-sec-Butylphenol (4-sec-BP) is an androgen receptor ligand that binds to the androgen receptor with a pIC50 of 4.07. 4-sec-Butylphenol is an estrogen receptor agonist. 4-sec-Butylphenol can be found in industrial effluents, in production water of oil and gas platforms, as well as in river water samples.
For research use only. We do not sell to patients.
- CAS No.: 99-71-8
- Formula: C10H14O
- Molecular Weight:150.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
4-sec-Butylphenol binds to the androgen receptor with an experimentally measured pIC50 of 4.07, which was predicted by the QSAR model to be 3.75[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 99-71-8
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Molecular Weight 150.22
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Formula C10H14O
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SMILES
OC1=CC=C(C=C1)C(C)CC
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Synonyms
4-sec-BP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hahn V, et al. Biotransformation of 4-sec-butylphenol by Gram-positive bacteria of the genera Mycobacterium and Nocardia including modifications on the alkyl chain and the hydroxyl group. Appl Microbiol Biotechnol. 2013 Sep;97(18):8329-39. [Content Brief]
[2]. Lill MA, et al. Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. J Med Chem. 2005;48(18):5666-5674. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-sec-Butylphenol Related Classifications
HY-W142795 Related Classifications
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