4-sec-Butylphenol
4-sec-Butylphenol (4-sec-BP) is an androgen receptor ligand that binds to the androgen receptor with a pIC50 of 4.07. 4-sec-Butylphenol is an estrogen receptor agonist. 4-sec-Butylphenol can be found in industrial effluents, in production water of oil and gas platforms, as well as in river water samples.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 99-71-8
- Formel: C10H14O
- Molecular Weight:150.22
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
4-sec-Butylphenol binds to the androgen receptor with an experimentally measured pIC50 of 4.07, which was predicted by the QSAR model to be 3.75[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 99-71-8
-
Molecular Weight 150.22
-
Formel C10H14O
-
SMILES
OC1=CC=C(C=C1)C(C)CC
-
Synonyms
4-sec-BP
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Hahn V, et al. Biotransformation of 4-sec-butylphenol by Gram-positive bacteria of the genera Mycobacterium and Nocardia including modifications on the alkyl chain and the hydroxyl group. Appl Microbiol Biotechnol. 2013 Sep;97(18):8329-39. [Content Brief]
[2]. Lill MA, et al. Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. J Med Chem. 2005;48(18):5666-5674. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
4-sec-Butylphenol Related Classifications
HY-W142795 Related Classifications
Powered by Bioz