1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. 5-HT6/5-HT2A receptor ligand-2

5-HT6/5-HT2A receptor ligand-2 

Cat. No.: HY-146077
Handling Instructions

5-HT6/5-HT2A receptor ligand-2 (compound 42) is a brain-penetrant dual 5-HT6/5-HT2A receptor antagonist, with a Ki of 25 nM and 32 nM, respectively. 5-HT6/5-HT2A receptor ligand-2 shows pro-cognitive properties.

For research use only. We do not sell to patients.

5-HT6/5-HT2A receptor ligand-2 Chemical Structure

5-HT6/5-HT2A receptor ligand-2 Chemical Structure

CAS No. : 2411088-16-7

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Description

5-HT6/5-HT2A receptor ligand-2 (compound 42) is a brain-penetrant dual 5-HT6/5-HT2A receptor antagonist, with a Ki of 25 nM and 32 nM, respectively. 5-HT6/5-HT2A receptor ligand-2 shows pro-cognitive properties[1].

IC50 & Target[1]

5-HT6 Receptor

25 nM (Ki)

5-HT2A Receptor

32 nM (Ki)

Molecular Weight

351.37

Formula

C20H18FN3O2

CAS No.
SMILES

OC1=CC=C(C2=CC=C(CNCCC3=CNC4=NC=C(F)C=C43)O2)C=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
5-HT6/5-HT2A receptor ligand-2
Cat. No.:
HY-146077
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