1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. Acamprosate calcium

Acamprosate calcium (Synonyms: Calcium N-acetylhomotaurinate)

Cat. No.: HY-17030 Purity: ≥98.0%
Handling Instructions

Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction.

For research use only. We do not sell to patients.

Acamprosate calcium Chemical Structure

Acamprosate calcium Chemical Structure

CAS No. : 77337-73-6

Size Price Stock Quantity
Solution
10 mM * 1 mL in Water USD 73 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 73 In-stock
Estimated Time of Arrival: December 31
Solid
50 mg USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. IC50 value: Target: GABA receptor Acamprosate, or N-acetyl homotaurine, is an N-methyl-D-aspartate receptor modulator approved by the Food and Drug Administration (FDA) as a pharmacological treatment for alcohol dependence.Acamprosate has low bioavailability, but also has an excellent tolerability and safety profile. In comparison with naltrexone and disulfiram, which are the other FDA-approved treatments for alcohol dependence, acamprosate is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so can be administered to patients with hepatitis or liver disease (a common comorbid condition among individuals with alcohol dependence) and to patients who continue drinking alcohol.

Clinical Trial
Molecular Weight

200.24

Formula

C₅H₁₀NO₄S . ₁/₂ Ca

CAS No.
SMILES

CC(NCCCS([O-])(=O)=O)=O.[0.5Ca2+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (499.40 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9940 mL 24.9700 mL 49.9401 mL
5 mM 0.9988 mL 4.9940 mL 9.9880 mL
10 mM 0.4994 mL 2.4970 mL 4.9940 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: ≥98.0%

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Keywords:

AcamprosateCalcium N-acetylhomotaurinateGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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Acamprosate calcium
Cat. No.:
HY-17030
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