1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. Afloqualone

Afloqualone 

Cat. No.: HY-B1833 Purity: >98.0%
Handling Instructions

Afloqualone is a agonist of GABA receptor .

For research use only. We do not sell to patients.

Afloqualone Chemical Structure

Afloqualone Chemical Structure

CAS No. : 56287-74-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
100 mg USD 72 In-stock
Estimated Time of Arrival: December 31
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Description

Afloqualone is a agonist of GABA receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. Afloqualone is an analogue of methaqualone. It has sedative and muscle-relaxant effects, resulting from its agonist activity at the β subtype of the GABAa receptor. in vivo: Afloqualone slightly increased the response during the alarm period in one out of 3 rats at 5, 10, and 20 mg/kg p.o., respectively.

Molecular Weight

283.30

Formula

C₁₆H₁₄FN₃O

CAS No.

56287-74-2

SMILES

O=C1N(C2=CC=CC=C2C)C(CF)=NC3=C1C=C(N)C=C3

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 33 mg/mL (116.48 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5298 mL 17.6491 mL 35.2983 mL
5 mM 0.7060 mL 3.5298 mL 7.0597 mL
10 mM 0.3530 mL 1.7649 mL 3.5298 mL
*Please refer to the solubility information to select the appropriate solvent.
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Afloqualone
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