CBB1003 hydrochloride
CBB1003 Hcl is a novel histone demethylase LSD1 inhibitor with IC50 of 10.
For research use only. We do not sell to patients.
- CAS No.: 2070015-02-8
- Formula: C25H36Cl5N9O4
- Molecular Weight:703.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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KDM1/LSD1 |
Chemical Information
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CAS No. 2070015-02-8
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Molecular Weight 703.88
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Formula C25H36Cl5N9O4
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SMILES
NC(N1CCN(CC2=CC(C(N3CCN(C(C4=CC=C(C(N)=N)C=C4)=O)CC3)=O)=CC([N+]([O-])=O)=C2)CC1)=N.[H]Cl.[H]Cl.[H]Cl.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang J, et al. Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties. Cancer Res. 2011 Dec 1;71(23):7238-49. [Content Brief]
[2]. Hsu HC, et al. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2014 Jul 25. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)