DHMEQ racemate
DHMEQ racemate is a NF-κB inhibitor. DHMEQ racemate is less active than (-)-DHMEQ.
For research use only. We do not sell to patients.
- CAS No.: 287194-38-1
- Formula: C13H11NO5
- Molecular Weight:522.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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NF-κB |
DHMEQ racemate (DHM3EQ) and (-)-DHMEQ (DHM2EQ) inhibits TNF-a-induced NF-kB activation. (-)-DHMEQ is more potent and less toxic than DHMEQ racemate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 287194-38-1
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Molecular Weight 522.47
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Formula C13H11NO5
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SMILES
O=C1[C@H]2[C@H](O2)[C@H](O)C(NC(C3=C(O)C=CC=C3)=O)=C1.O=C4[C@@H](O5)[C@@H]5[C@@H](O)C(NC(C6=C(O)C=CC=C6)=O)=C4
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Synonyms
rel-DHMEQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : ≥ 32 mg/mL (61.25 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9140 mL | 9.5699 mL | 19.1399 mL | 47.8496 mL |
| 5 mM | 0.3828 mL | 1.9140 mL | 3.8280 mL | 9.5699 mL | |
| 10 mM | 0.1914 mL | 0.9570 mL | 1.9140 mL | 4.7850 mL | |
| 15 mM | 0.1276 mL | 0.6380 mL | 1.2760 mL | 3.1900 mL | |
| 20 mM | 0.0957 mL | 0.4785 mL | 0.9570 mL | 2.3925 mL | |
| 25 mM | 0.0766 mL | 0.3828 mL | 0.7656 mL | 1.9140 mL | |
| 30 mM | 0.0638 mL | 0.3190 mL | 0.6380 mL | 1.5950 mL | |
| 40 mM | 0.0478 mL | 0.2392 mL | 0.4785 mL | 1.1962 mL | |
| 50 mM | 0.0383 mL | 0.1914 mL | 0.3828 mL | 0.9570 mL | |
| 60 mM | 0.0319 mL | 0.1595 mL | 0.3190 mL | 0.7975 mL |