1. Metabolic Enzyme/Protease
  2. Proteasome
    Endogenous Metabolite
  3. Isovalerylcarnitine

Isovalerylcarnitine 

製品番号: HY-113221 純度: ≥99.0%
COA 取扱説明書

Isovalerylcarnitine is a product of the catabolism of L-leucine. Isovalerylcarnitine is also a selective and reversible calpain activator that induces apoptosis.

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Isovalerylcarnitine 構造式

Isovalerylcarnitine 構造式

CAS 番号 : 31023-24-2

容量 価格(税別) 在庫状況 数量
5 mg USD 100 在庫あり
Estimated Time of Arrival: December 31
10 mg   お問い合わせ  
50 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of Isovalerylcarnitine:

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製品説明

Isovalerylcarnitine is a product of the catabolism of L-leucine. Isovalerylcarnitine is also a selective and reversible calpain activator that induces apoptosis[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

体外実験

Isovalerylcarnitine produces an early and marked increase in phagocytosis and also in cell killing, as well as reduces proliferation, in U937 leukemic cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

245.32

Appearance

Solid

分子式

C12H23NO4

CAS 番号
SMILES

CC(C)CC(O[[email protected]](CC([O-])=O)C[N+](C)(C)C)=O

Structure Classification
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度
体外: 

H2O : 100 mg/mL (407.63 mM; Need ultrasonic)

DMSO : 50 mg/mL (203.82 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0763 mL 20.3815 mL 40.7631 mL
5 mM 0.8153 mL 4.0763 mL 8.1526 mL
10 mM 0.4076 mL 2.0382 mL 4.0763 mL
*Please refer to the solubility information to select the appropriate solvent.
体内:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution

*All of the co-solvents are available by MCE.
純度とドキュメンテーション

純度: ≥99.0%

参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

製品名:
Isovalerylcarnitine
製品番号:
HY-113221
数量:
MCE 日本正規代理店: