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Kinase inhibitor-1 

Cat. No.: HY-43533 Purity: 99.33%
Handling Instructions

Kinase inhibitor-1 (Compound 5) is a kinase inhibitor.

For research use only. We do not sell to patients.

Kinase inhibitor-1 Chemical Structure

Kinase inhibitor-1 Chemical Structure

CAS No. : 2135696-72-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 495 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

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Description

Kinase inhibitor-1 (Compound 5) is a kinase inhibitor[1].

IC50 & Target

Kinase[1]

In Vitro

Kinases represent a large family of enzymes that catalyse the phosphorylation of proteins, lipids and metabolites and play a central role in the regulation of a wide variety of cellular processes. Abnormal kinase activity has been related to a wide range of disorders, including cancers[1].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (216.57 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1657 mL 10.8286 mL 21.6572 mL
5 mM 0.4331 mL 2.1657 mL 4.3314 mL
10 mM 0.2166 mL 1.0829 mL 2.1657 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.41 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.41 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

461.74

Formula

C₁₉H₁₈BrClN₆O

CAS No.

2135696-72-7

SMILES

BrC1=C(Cl)C=CC(NC2=NC=NC3=CN=C(NC(/C=C/CN(C)C)=O)C=C32)=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Kinase inhibitor-1
Cat. No.:
HY-43533
Quantity:

Kinase inhibitor-1

Cat. No.: HY-43533