1. GPCR/G Protein
    Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. M40

M40 

Cat. No.: HY-P1025 Purity: 98.25%
Handling Instructions

M40 is a potent, non-selective galanin receptor antagonist.

For research use only. We do not sell to patients.

M40 Chemical Structure

M40 Chemical Structure

CAS No. : 143896-17-7

Size Price Stock Quantity
500 μg USD 168 In-stock
Estimated Time of Arrival: December 31
1 mg USD 252 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1008 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1440 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

M40 is a potent, non-selective galanin receptor antagonist.

In Vitro

M40 (1 μM) displaces [mono[125IJodo-Tyr26]galanin from binding sites in the hippocampus, hypothalamus, and spinal cord. M40 has a lower affinity than galanin for all membranes. The IC50 values are 6 nM in the hippocampus, 15 nM in the hypothalamus, 12 nM in the spinal cord, and 3 nM in the insulinoma cells. M40 (1 μM) completely blocks 125I-labeled galanin-binding sites[1].

Molecular Weight

1980.31

Formula

C₉₅H₁₄₆N₂₂O₂₄

CAS No.

143896-17-7

Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2

Sequence Shortening

GWTLNSAGYLLGPPPALALA-NH2

SMILES

[GWTLNSAGYLLGPPPALALA-NH2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

M40M 40M-40Neuropeptide Y ReceptorNPY receptorInhibitorinhibitorinhibit

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