1. GPCR/G Protein
  2. Neuropeptide Y Receptor

M40 (Synonyms: GWTLNSAGYLLGPPPALALA)

Cat. No.: HY-P1025 Purity: 98.25%
Handling Instructions

M40 is a potent, non-selective galanin receptor antagonist.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

M40 Chemical Structure

M40 Chemical Structure

CAS No. : 143896-17-7

Size Price Stock Quantity
500 ug USD 168 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
1 mg USD 252 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 1008 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 1440 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

M40 is a potent, non-selective galanin receptor antagonist.

In Vitro

M40 (1 μM) displaces [mono[125IJodo-Tyr26]galanin from binding sites in the hippocampus, hypothalamus, and spinal cord. M40 has a lower affinity than galanin for all membranes. The IC50 values are 6 nM in the hippocampus, 15 nM in the hypothalamus, 12 nM in the spinal cord, and 3 nM in the insulinoma cells. M40 (1 μM) completely blocks 125I-labeled galanin-binding sites[1].

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 0.5050 mL 2.5249 mL 5.0497 mL
5 mM 0.1010 mL 0.5050 mL 1.0099 mL
10 mM 0.0505 mL 0.2525 mL 0.5050 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1980.31

Formula

C₉₅H₁₄₆N₂₂O₂₄

CAS No.

143896-17-7

SMILES

OC(C=C1)=CC=C1C[[email protected]@H](C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CC(C)C)C(NCC(N2[[email protected]@H](CCC2)C(N3[[email protected]@H](CCC3)C(N4[[email protected]@H](CCC4)C(N[[email protected]@H](C)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](C)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(CNC([[email protected]](C)NC([[email protected]](CO)NC([[email protected]](CC(N)=O)NC([[email protected]](CC(C)C)NC([[email protected]@]([[email protected]](O)C)([H])NC([[email protected]@H](CC(CN)=O)CC5=CNC6=C5C=CC=C6)=O)=O)=O)=O)=O)=O)=O

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
M40
Cat. No.:
HY-P1025
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