Pulchinenoside C  (Synonyms: Anemoside B4)

Pulchinenoside C (Anemoside B4) is Pulsatilla koreana Nakai that have many numerous biological effects in vitro, including enhancing hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.

Pulchinenoside C (Anemoside B4) can inhibit the secretion of IL-10; SSA, SSD and PNS up-regulated IL-2 expression^[1]. Pulchinenoside C (Anemoside B4), with IC50 value more than 390 ug/mL. Anemoside B4 inhibits cell proliferation^[2]. Pulchinenoside C (Anemoside B4) can significantly suppress the secretion of the inflammatory factor E-selectin by endothelial cells^[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1221.38

Solid

C₅₉H₉₆O₂₆

129741-57-7

O=C([C@]1(CC[C@H]2C(C)=C)[C@@]2([H])[C@](CC[C@@]3([H])[C@]4(CC[C@]5([H])[C@@]3(CC[C@H](O[C@@](OC[C@H](O)[C@@H]6O)([H])[C@@H]6O[C@@](O[C@@H](C)[C@H](O)[C@H]7O)([H])[C@@H]7O)[C@@]5(C)CO)C)C)([H])[C@@]4(C)CC1)O[C@@H]([C@@H]([C@@H](O)[C@@H]8O)O)O[C@@H]8CO[C@@H]([C@@H]([C@@H](O)[C@@H]9O[C@@](O[C@@H](C)[C@H](O)[C@H]%10O)([H])[C@@H]%10O)O)O[C@@H]9CO

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Hu Y et al. Role of Chinese herbal medicinal ingredients in secretion of cytokines by PCV2-induced endothelial cells. J Immunotoxicol. 2016;13(2):141-7.  [Content Brief]

  [2]. Liu M et al. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid. Pharm Biol. 2015 Jan;53(1):1-9.  [Content Brief]

  [3]. Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. Immunopharmacol Immunotoxicol. 2009;31(4):550-5.  [Content Brief]