1. Metabolic Enzyme/Protease
  2. ROR

RORγt Inverse agonist 2 

Cat. No.: HY-111748
Handling Instructions

RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM.

For research use only. We do not sell to patients.

RORγt Inverse agonist 2 Chemical Structure

RORγt Inverse agonist 2 Chemical Structure

CAS No. : 1801197-92-1

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM[1].

IC50 & Target

EC50: 119 nM (RORγt)[1]

In Vitro

RORγt Inverse agonist 2 (Compound 26) is inactive against RORα and RORβ in either inverse agonist or agonist mode (>40 μM)[1].

References
Molecular Weight

627.54

Formula

C₂₇H₂₅F₈NO₅S

CAS No.

1801197-92-1

SMILES

FC(C(F)(F)F)(C(F)(F)F)C1=CC=C([[email protected]]2(CN(C([[email protected]@H]3CC[[email protected]@H](C(O)=O)CC3)=O)CC2)S(C4=CC=C(F)C=C4)(=O)=O)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
RORγt Inverse agonist 2
Cat. No.:
HY-111748
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RORγt Inverse agonist 2

Cat. No.: HY-111748