Infection

CDA-IN-5 (Compound M-09) is a Chitin deacetylase inhibitor with a K_i of 27.5 μM against PstCDA. CDA-IN-5 is an antifungal agent. CDA-IN-5 can inhibit infection by Rhizoctonia solani, Pyricularia oryzae, and Botrytis cinerea and exhibits moderate control efficacy against rice sheath blight.

CGP-75355 is an inhibitor of HIV-1 protease with IC₅₀ of 26 nM. CGP-75355 is a bis(L-tert-leucine) derivative.

10-Deoxymethymycin (Antibiotic YC 17) displays antibiotic activity against Gram positive bacteria.

Lazertinib (Standard) is the analytical standard of Lazertinib (HY-109061). This product is intended for research and analytical applications. Lazertinib (YH25448) is a potent, selective, CNS-penetrant, orally available and irreversible EGFR tyrosine K_inase inhibitor, exhibiting high selectivity for activating (EGFRm) and T790M resistance mutations. Lazertinib inhibits phosphorylation of EGFR, AKT and ERK, leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. Lazertinib can be used in the study of non-small cell lung cancer.

U18666A (Standard) is the analytical standard of U18666A (HY-107433). This product is intended for research and analytical applications. U18666A, an intra-cellular cholesterol transport inhibitor, inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.

Pyloricidin C is an antibiotic against Helicobacter pylori found in Bacillus sp. HC-70.

Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.

Usaramine (Standard) is the analytical standard of Usaramine. This product is intended for research and analytical applications. Usaramine is a pyrrolizidine alkaloid isolated from seeds of Crolatalaria pallida. Usaramine demonstrates a highlighted antibiofilm activity against Staphylococcus epidermidis by reducing more than 50% of biofilm formation without killing the bacteria.

Halymecin A is an antibiotic found in Marine microbes. Halymecin A had only weak antibacterial and fungal activity.

Prolylrapamycin (21-Norrapamycin) is the derivative of Rapamycin (HY-10219). Prolylrapamycin exhibits antifungal activity, that inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC of 0.125-2 μg/mL.

Tamarixin is flavonoid that isolated from Astragalus tanae Sosn that has hepatoprotective, antioxidant, anticancer, and antimicrobial activities.

TMV-IN-11 (compound syn-3g) is a potent TMV inhibitor with high inactivation capacity (IC₅₀: 120.7 μg/mL). TMV-IN-11 can effectively inhibit the expression of TMV.

2-Hydroxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[.

Primocarcin is an antibiotic that inhibits Ehrlich ascites cancer.

Arphamenine B is a Zn²⁺-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B enhances the immune response and is used to characterize novel proteases.

hERG-IN-1 (compound 2a) is an antibacterial agent and inhibitor of hERG. hERG-IN-1 inhibits pulmonary infection caused by Pseudomonas aeruginosa strain ATCC 27853.

Janthinocin A has strong activity of anti-Gram-positive bacteria and moderate anti-Gram-negative bacteria.

Flutianil is a fungicide, which specifically inhibits the powdery mildew species. Flutianil inhibits the haustorium formation and subsequent mycelia growth.

Isonardoperoxide is a potent antimalaria agent with an EC₅₀ of 0.6 μM for Plasnwdium fulciparum malaria.

Tobramycin (Nebramycin Factor 6) monosulfate is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms. Tobramycin monosulfate can be used to pneumonia research caused by Pseudomonas aeruginosa.