Others

Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM

L-Allooctopine is a competitive inhibitor of D-octopine.

Tetrazolium violet is a redox indicator commonly used in various biochemical assays to measure cell viability and metabolic activity. Tetrazolium Violet has unique chemical properties that allow it to be reduced by cellular enzymes such as dehydrogenases to form a purple formazan product that can be detected spectrophotometrically. This makes it a useful tool for assessing cell health and growth in culture or tissue samples.

3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking.

(S,R,S)-CO-C2-acid (VH 032 amide-alkylC2-acid) is a functionalized von-Hippel-Lindau (VHL) protein ligand and linker conjugate, which can be used in the research and development of PROTACs.

SPHINX is a selective SRPK1 inhibitor with an IC₅₀ value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD.

Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization.

MEIS-IN-1 is a potent myeloid ecotropic viral integration site (MEIS) inhibitor to induce murine and human hematopoietic stem-cell expansion.

TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate.

(R)-M8891 is the low-activity isomer of M8891 (HY-133016). M8891 is an orally active, reversible, and blood-brain barrier-penetrant methionine aminopeptidase 2 (MetAP-2) inhibitor.

Clothianidin-d₃ is the deuterium labeled Clothianidin.Clothianidin-d₃ is a neonicotinoid insecticide. Clothianidin-d₃ shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d₃ has various application methods and high safety for crops.

ent-Florfenicol amine-d₃ is deuterated labeled ent-Florfenicol amine.

Levofloxacin N-oxide is an oxidation product and impurity of Levofloxacin (HY-B0330), and it is a non-mutagen. Under specific concentration conditions with the addition of S-9 mixture, Levofloxacin N-oxide increases structural chromosomal aberrations in hamster lung cells.

trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine.

Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate (16:0-18:1 PA) is an anionic phospholipid containing a monounsaturated acyl chain. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate exhibits activity in modulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is used in the preparation of micelles, liposomes, and other types of artificial membranes.

Celecoxib carboxylic acid is a metabolite of celecoxib (HY-14398). Celecoxib is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

8-Nitroguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).

N-Benzoyl-L-tyrosine p-nitroanilide is a chymotrypsin substrate.

Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes, reduces hyperpigmentation and thus ameliorates melasma lesions and solar lentigines.