2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Cytochrome P450
  5. CYP11 Isoform
  6. CYP11 Inhibitor

CYP11 Inhibitor

CYP11 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-101217
    BI 689648
    		Inhibitor 99.20%
    BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively.
  • HY-135281
    CYP11B2-IN-1
    		Inhibitor 99.83%
    CYP11B2-IN-1 is a CYP11B2 inhibitor with an IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with an IC50 of 142 nM.
  • HY-151140
    CYP11B1-IN-2
    		Inhibitor
    CYP11B1-IN-2 (compound 7aa) is an orally active, potent and selective CYP11B1 inhibitor, with IC50 values of 9 nM and 25 nM for human CYP11B1 and rat CYP11B1, respectively. CYP11B1-IN-2 can be used for the research of diseases caused by excessive cortisol.