Fungal
An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.
Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.
All Product Categories
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Fungal Related Products (2768)
Related Products (2768)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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Methyl 3-hydroxy-4,5-dimethoxybenzoate
0 ImagesMethyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant that can be isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2.
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(Rac)-Dehydrocostus Lactone
0 ImagesSynonyms: (Rac)-Epiligulyl oxide(Rac)-Dehydrocostus Lactone ((Rac)-Epiligulyl oxide) is a natural product with antiparasitic activity. (Rac)-Dehydrocostus Lactone can significantly inhibit the growth of Trypanosoma brucei rhodesiense. (Rac)-Dehydrocostus Lactone exhibits a broad spectrum of biological effects, including anti-inflammatory, anticancer, antiviral and antimicrobial activities. (Rac)-Dehydrocostus Lactone also has antifungal, antioxidant, antidiabetic, antiulcer and antihelminthic effects. (Rac)-Dehydrocostus Lactone exhibits different IC(50) values in cytotoxicity tests and has a high selectivity index.
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Sinigrin hydrate
0 ImagesSynonyms: Allyl-glucosinolate hydrate; 2-Propenyl-glucosinolate hydrateSinigrin (Allyl-glucosinolate) hydrate is an orally active glucosinolate found in cruciferous plants. Sinigrin hydrate possesses multiple activities such as anti-cancer, antibacterial, antifungal, anti-inflammatory, antioxidant, and inhibition of fat synthesis. Sinigrin hydrate can be used in the research of tumors, inflammatory, and metabolic diseases.
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Eberconazole nitrate
0 ImagesEberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis.
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CRAMP-18 (mouse) acetate
0 ImagesCat. No.: HY-P5016APurity: 99.33%CRAMP-18 (mouse) acetate is an antibiotic peptide without hemolytic activity. CRAMP-18 (mouse) acetate has good inhibitory activity against Gram-negative bacteria, such as S. typhimurium and P. aeruginosa. CRAMP-18 (mouse) acetate has the potential to study antifungal, antibacterial and antitumor.
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Cymoxanil
0 ImagesCymoxanil is a fungicidal cyanooxime against plant diseases caused by fungi belonging to the Perenosporales. Cymoxanil affects growth, DNA and RNA synthesis in Phytophthora.
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Cyprodinil (Standard)
0 ImagesSynonyms: CGA-219417 (Standard)Cyprodinil (Standard) (CGA-219417 (Standard)) is the analytical standard of Cyprodinil (HY-116214). This product is intended for research and analytical applications. Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens.
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3-Hydroxy-4-methoxycinnamaldehyde
0 Images3-Hydroxy-4-methoxycinnamaldehyde (compound 2) is a cinnamaldehyde from the stem bark of Flemingia paniculata Wall. 3-Hydroxy-4-methoxycinnamaldehyde exhibits antibacterial (both Gram-positive and Gram-negative) and antifungal activities (MIC = 12.5-50 μg/mL). 3-Hydroxy-4-methoxycinnamaldehyde can be used for microbial infections research.
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Tetradehydropodophyllotoxin
0 ImagesSynonyms: DehydropodophyllotoxinTetradehydropodophyllotoxin possesses antifungal activity.
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Thalifoline
0 ImagesThalifoline is an isoquinoline alkaloid. Thalifoline exerts cytotoxic effects on cancer cells. Thalifoline inhibits the growth of Fusarium oxysporum f. sp. lycopersici. Thalifoline can be used in research related to lung adenocarcinoma, colon cancer, oral epidermoid carcinoma, and fungal infections.
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Caffeic acid-13C3
0 ImagesSynonyms: 3,4-Dihydroxycinnamic acid-13C3Caffeic acid-13C3 is an 13C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses.
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Norsanguinarine
0 ImagesNorsanguinarine is a benzophenanthridine-type isoquinoline alkaloid and plant pathogenic Fungal spore germination inhibitor. Norsanguinarine is an intermediate in the biosynthetic process of sanguinarine-type alkaloids in poppy calli. Norsanguinarine is present in the whole plant of Eschscholtzia californica and calli of Papaver somniferum L. Norsanguinarine inhibits spore germination of Alternaria brassicicola and Curvularia maculans. Norsanguinarine can be used in studies related to plant pathogenic fungal infections.
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Pseudolaric acid A-O-β-D-glucopyranoside
0 ImagesPseudolaric acid A-O-β-D-glucopyranoside, isolated from Cortex Pseudolaricis, demonstrates antifungal and antifertility activities.
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Prodigiosin hydrochloride
0 ImagesSynonyms: Prodigiosine hydrochlorideProdigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties.
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Thymol iodide
0 ImagesThymol iodide is an iodine derivative of thymol, serving as a mild preservative and fungicide. Thymol iodide is commonly used as an iodine source in the intensive culture of rotifers. Thymol iodide effectively enables Brachionus "Cayman" rotifers to reach iodine levels similar to those of copepods, and maintains a high iodine content during storage. After 28 days of intrapleural injection of Thymol iodide, it does not enhance the efficacy of inducing pleurodesis in rabbits, nor does it improve the efficacy of talc slurry pleurodesis.
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Oligomycin E
0 ImagesCat. No.: HY-125300CAS No.: 110231-34-0Oligomycin E is a antitumor antibiotic that can be isolated from Streptomyces. Oligomycin E has significant antifungal activity, showing minimal inhibitory concentrations (MICs) values between 2 and 75μg/mL. Oligomycin E has strong antitumor activity against HeLa cells, with an IC50 of 0.014 μg/mL.
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Orysastrobin
0 ImagesCat. No.: HY-111968CAS No.: 248593-16-0Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice.
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Pyromeconic acid
0 ImagesPyromeconic acid is an antifungal substance.
