2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-6 Isoform
  6. IL-6 Inhibitor

IL-6 Inhibitor

IL-6 Inhibitors (39):

Cat. No. Product Name Effect Purity
  • HY-11109
    Resatorvid
    		Inhibitor 99.95%
    Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor.
  • HY-102084
    LMT-28
    		Inhibitor 98.85%
    LMT-28 is an orally active and the first synthetic IL-6 inhibitor that functions through direct binding to gp130.
  • HY-B1402
    Hydrocortisone hemisuccinate
    		Inhibitor 99.76%
    Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti-inflammatory drug (SAID).
  • HY-P99210
    Olokizumab
    		Inhibitor
    Olokizumab (CDP 6038) is a humanized monoclonal antibody targeting the interleukin-6 (IL-6).
  • HY-N8884
    Coelonin
    		Inhibitor
    Coelonin is a dihydrophenanthrene with anti-inflammation activity.
  • HY-N4028
    Hydrangenol
    		Inhibitor
    Hydrangenol is an orally active antiphotoaging compound.
  • HY-15614
    SC144
    		Inhibitor 98.50%
    SC144 is a first-in-class, orally active gp130 (IL6-beta) inhibitor.
  • HY-N0633
    Muscone
    		Inhibitor ≥98.0%
    Muscone is the main active monomer of traditional Chinese medicine musk.
  • HY-15509A
    Semapimod tetrahydrochloride
    		Inhibitor 98.43%
    Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6.
  • HY-N0619
    Mulberroside A
    		Inhibitor 99.75%
    Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.
  • HY-15614A
    SC144 hydrochloride
    		Inhibitor 99.34%
    SC144 hydrochloride is a first-in-class, orally active gp130 (IL6-beta) inhibitor.
  • HY-N0569
    Madecassic acid
    		Inhibitor 99.23%
    Madecassic acid is isolated from Centella asiatica (Umbelliferae).
  • HY-107390
    AX-024
    		Inhibitor 99.29%
    AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM.
  • HY-P1110
    AF12198
    		Inhibitor 99.75%
    AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM).
  • HY-N0314
    Pectolinarin
    		Inhibitor 99.89%
    Pectolinarin possesses anti-inflammatory activity.
  • HY-N0604
    Ginsenoside Rh1
    		Inhibitor ≥98.0%
    Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.
  • HY-107390A
    AX-024 hydrochloride
    		Inhibitor 99.12%
    AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM.
  • HY-B0513
    Methylthiouracil
    		Inhibitor ≥98.0%
    Methylthiouracil is an antithyroid agent.
  • HY-B0667
    Balsalazide
    		Inhibitor 99.34%
    Balsalazide could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.
  • HY-B0446
    Naphazoline hydrochloride
    		Inhibitor 98.37%
    Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist.