2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. JNK
  5. JNK Degrader

JNK Degrader

JNK Isoform Comparison

JNK Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-182796
    JNK1 degrader-1
    		Degrader
    JNK1 degrader-1 is a JNK1 HyT degrader. JNK1 degrader-1 can induce JNK1 degradation through the HyT-mediated ubiquitin-proteasome system and autophagy-lysosome pathway. JNK1 degrader-1 inhibits TGF-β1-induced epithelial-mesenchymal transition (EMT). JNK1 degrader-1 can be used for research on fibrotic diseases and cancer metastasis. (Pink: JNK1 ligand (HY-183006); Blue: Hyt hydrophobic group (HY-W037848); Black: Linker (HY-B1008)).
  • HY-170601
    PROTAC JNK1 Degrader-1
    		Degrader
    PROTAC JNK1 Degrader-1 is a JNK1 PROTAC degrader with a DC50 of 10 nM. PROTAC JNK1 Degrader-1 reduces the level of fibronectin. PROTAC JNK1 Degrader-1 can be used for the research of pulmonary fibrosis.