2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Epigenetics
  4. PARP
  5. PARP Ligand

PARP Ligand

PARP Isoform Comparison

PARP Ligands (2):

Cat. No. Product Name Effect Purity
  • HY-160937
    AZD-9574-acid
    		Ligand 99.44%
    AZD-9574-acid (Compound 70D) is a PARP-1 ligand. AZD-9574-acid serves as a Ligand for Target Protein for PROTAC for the synthesis of PARP-1 PROTAC degraders. AZD-9574-acid is applicable to cancer research.
  • HY-183548
    XW-17
    		Ligand
    XW-17 is a PARP14 inhibitor with an IC50 of 3.03 nM and selectivity over other PARP family members.XW-17 suppresses PARP14-mediated mono-ADP-ribosylation, engages and stabilizes endogenous PARP14 protein.XW-17 attenuates skin lesions and decreases expression of IL-4, IL-13, IgE, and IL-17A in an atopic dermatitis-like mouse model.XW-17 can be used for the research of atopic dermatitis.