Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2540)
Related Products (2540)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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PfPK6-IN-1
0 ImagesCat. No.: HY-175215CAS No.: 2417648-94-1PfPK6-IN-1 is a potent and selective PfPK6 inhibitor with an IC50 of 0.3 μM. PfPK6-IN-1 inhibits hemozoin formation, a Plasmodium-specific pathway with IC50 of 13 μM against β-hematin (βH). PfPK6-IN-1 exhibits rapid and broad-spectrum anti-malarial properties, being effective against both chloroquine-sensitive and resistant strains.PfPK6-IN-1 can be used for the study of antimalarial.
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GNF179 (Metabolite)
0 ImagesCat. No.: HY-15980CAS No.: 1310455-86-7GNF179 metabolite is the metabolite of GNF179, which is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
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4,5-Dihydropiperlonguminine
0 Images4,5-Dihydropiperlonguminine is a natural product that can be isolated from the seeds of Piper tuberculatum Jacq. (Piperaceae). 4,5-Dihydropiperlonguminine is a insecticide against velvetbean caterpillars.
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Sutidiazine
0 ImagesCat. No.: HY-148177CAS No.: 1821293-40-6Synonyms: ZY-19489; MMV 253; AZ13721412Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect.
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Imidocarb dipropionate (Standard)
0 ImagesImidocarb (dipropionate) (Standard) is the analytical standard of Imidocarb (dipropionate). This product is intended for research and analytical applications. Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL.
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Tetrasul (Standard)
0 ImagesCat. No.: HY-124901RCAS No.: 2227-13-6Tetrasul (Standard) is the analytical standard of Tetrasul. This product is intended for research and analytical applications. Tetrasul is an acaricide. Tetrasul inhibits Tetranychus urticae and aphids on hops. Tetrasul has also been used in research of erythematous (type one) rosacea.
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SCR0911
0 ImagesCat. No.: HY-182711CAS No.: 1379615-30-1SCR0911 is an inhibitor of mycobacterial cytochrome bcc oxidase and Plasmodium falciparum cytochrome bc1. SCR0911 disrupts oxidative phosphorylation by binding to mycobacterial cytochrome bcc, binds to the Qi site of Plasmodium falciparum cytochrome bc1, inhibits mycobacterial cell growth and ATP synthesis, and exhibits broad-spectrum anti-mycobacterial and anti-malarial activities. SCR0911 can be used in research related to tuberculosis, malaria, and isolated persistent hypermethioninemia (iph).
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Liposomal Amphotericin B
0 ImagesCat. No.: HY-177849Synonyms: Amphotericin B liposomeLiposomal Amphotericin B (Amphotericin B liposome) is a liposomal formulation of Amphotericin B (HY-B0221) that can cross the blood-brain barrier. Liposomal Amphotericin B binds to fungal cell walls and releases Amphotericin B to bind Ergosterol (HY-N0181), inducing pore formation, ion leakage, and fungal cell death. Liposomal Amphotericin B exhibits fungicidal activity against a broad spectrum of fungal pathogens, also shows activity against Leishmania, and the liposomal formulation has lower acute and chronic toxicity as well as a lower risk of fungal resistance.
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DDD85646 (Standard)
0 ImagesCat. No.: HY-103056RCAS No.: 1215010-55-1Synonyms: IMP-366 (Standard)DDD85646 (Standard) is the analytical standard of DDD85646 (HY-103056). This product is intended for research and analytical applications. DDD85646 (IMP-366) is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nM; hNMT IC50=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis.
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Anticoccidial agent-2
0 ImagesCat. No.: HY-183532CAS No.: 189442-08-8Anticoccidial agent-2 is an orally effective imidazole-based anticoccidial agent. Anticoccidial agent-2 exhibits activity against Eimeria tenella in chickens. Anticoccidial agent-2 can be used in research related to chicken cecal coccidiosis.
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IMDNQ1
0 ImagesCat. No.: HY-112453CAS No.: 623163-52-0IMDNQ1 is a Trypanosoma cruzi inhibitor derived from 1,4-naphthoquinone substituted with cyclic imide. IMDNQ1 effectively inhibits the proliferation of Trypanosoma cruzi epimastigotes, while also reducing the viability of mouse fibroblasts. The selectivity index between the antiproliferative activity and cytotoxicity of IMDNQ1 is 60.25, indicating a certain level of safety. IMDNQ1 can be widely used in studies related to Chagas disease.
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N-Methylbenzo[d]oxazol-2-amine
![N-Methylbenzo[d]oxazol-2-amine](https://file.medchemexpress.com/product_pic/hy-w158234.gif "Click to View N-Methylbenzo[d]oxazol-2-amine Product Detail")
0 ImagesN-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism.
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TH7299
0 ImagesCat. No.: HY-148014CAS No.: 1415648-20-2TH7299 is a TbFolD inhibitor with antiparasitic activity. TH7299 binds the tetrahydrofolate-binding pocket of MTHFD2, and inhibits MTHFD2L and the dehydrogenase/cyclohydrolase domain of MTHFD1. TH7299 reduces cancer cells viability, induces apoptosis, DNA damage. TH7299 can be used for the researches of african trypanosomiasis and acute myeloid leukemia.
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SufS-IN-1
0 ImagesCat. No.: HY-175181CAS No.: 167933-78-0SufS-IN-1, a (2R,3R)-3-ethoxycarbonylaziridine-2-carboxylic acid (EAC), is a selective Cysteine desulfurase type II (SufS) inhibitor. SufS-IN-1 significantly inhibits the SufS activity by covalently binding to the cofactor PLP to form a stable PLP-ligand conjugates. SufS-IN-1 can be used for pathogenic microorganisms research, such as Plasmodium falciparum, Staphylococcus aureus and Mycobacterium tuberculosis.
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OfChi-h-IN-2
0 ImagesCat. No.: HY-157037CAS No.: 902932-91-6OfChi-h-IN-2 (compound TQ19) is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-2 can significantly inhibit the growth and development of Ostrinia nubilalis larvae. OfChi-h-IN-2 can be used in agricultural insecticide research.
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α-Thujone (Standard)
0 ImagesCat. No.: HY-121618RCAS No.: 546-80-5α-Thujone (Standard) is the analytical standard of α-Thujone. This product is intended for research and analytical applications. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier.
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Buparvaquone (Standard)
0 ImagesBuparvaquone (Standard) is the analytical standard of Buparvaquone. This product is intended for research and analytical applications. Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.
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Chloroxylenol (Standard)
0 ImagesChloroxylenol (Standard) is the analytical standard of Chloroxylenol. This product is intended for research and analytical applications. Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses.
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Diiodohydroxyquinoline (Standard)
0 ImagesSynonyms: Iodoquinol (Standard); 5,7-Diiodo-8-hydroxyquinoline (Standard); 5,7-Diiodo-8-quinolinol (Standard)Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas.
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SPB07935
0 ImagesCat. No.: HY-173027CAS No.: 634190-75-3SPB07935 inhibits the plasmepsin II in Plasmodium falciparum and can be used as an antimalarial agent. SPB07935 regulates the life cycle of P. falciparum, inhibits the growth of Plasmodium strains FcB1 and 3D7 with IC50 of 8 μM and 4.7 μM.
