Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2530)
Related Products (2530)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Epsiprantel
0 ImagesCat. No.: HY-U00045CAS No.: 98123-83-2Synonyms: BRL-38705Epsiprantel (BRL-38705) is a compound with anti-Echinococcus activity that can cause the death of protoscolex, larvae and adults in vitro, and is more effective against mature worms than larvae in vivo, with no side effects.
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Pyriproxyfen-d4
0 ImagesCat. No.: HY-B2031S1CAS No.: 2446366-95-4Synonyms: S-31183-d4Pyriproxyfen-d4 (S-31183-d4) is the deuterium labeled Pyriproxyfen. Pyriproxyfen is a juvenile hormone analog and insect growth regulator. Pyriproxyfen is used in research related to dengue fever and malaria.
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Benznidazole-d7
0 ImagesCat. No.: HY-B1548SSynonyms: Benznidazol-d7; Ro 07-1051-d7; Ro 71051-d7Benznidazole-d7 (Benznidazol-d7; Ro 07-1051-d7; Ro 71051-d7) is the deuterium labeled Benznidazole (HY-B1548). Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
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Sulfaquinoxaline (Standard)
0 ImagesSulfaquinoxaline (Standard) is the analytical standard of Sulfaquinoxaline. This product is intended for research and analytical applications. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections.
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Isochamaejasmin
0 ImagesCat. No.: HY-N3497CAS No.: 93859-63-3Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells. Isochamaejasmin also has a moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) and relatively low cytotoxicity (CC50 of 29.0 μM).
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Moxidectin (Standard)
0 ImagesCat. No.: HY-B0777RCAS No.: 113507-06-5Synonyms: CL301423 (Standard)Moxidectin (Standard) is the analytical standard of Moxidectin. This product is intended for research and analytical applications. Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk.
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Flufenamic acid-d4
0 ImagesCat. No.: HY-B1221SCAS No.: 1185071-99-1Flufenamic acid-d4 is deuterium labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
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MK 436
0 ImagesCat. No.: HY-117129CAS No.: 33450-08-7Synonyms: MK-0436MK 436 (MK-0436) is a metabolite with anti-trypanosomal activity that can be isolated from dog urine, particularly effective against Trypanosoma cruzi, the pathogen responsible for Chagas disease in South America.
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Insecticidal agent 11
0 ImagesCat. No.: HY-P10390CAS No.: 1798816-86-0Insecticidal agent 11 (compound Q6) is a potent insect growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella.
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Quinoprazine
0 ImagesCat. No.: HY-147371CAS No.: 115618-99-0Quinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC50 value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrPSc levels-.
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Palmatine chloride (Standard)
0 ImagesPalmatine (chloride) (Standard) is the analytical standard of Palmatine (chloride). This product is intended for research and analytical applications. Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities.
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Empenthrin
0 ImagesCat. No.: HY-121328CAS No.: 54406-48-3Synonyms: S-2852FEmpenthrin (S-2852F) is a synthetic pyrethroid. Empenthrin can be used in insecticides. Empenthrin shows a clear species-specificity in the inhibitory effect on the Pentobarbital (PTB)-metabolizing enzyme(s). Empenthrin prolongs PTB induced-sleeping time in mice through an inhibition of the PTB-metabolizing enzyme(s) in the liver, an effect that does not occur in rats. Empenthrin shows a clear species-specificity in the inhibitory effect on the PTB-metabolizing enzyme(s).
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6-O-Methacrylate
0 ImagesCat. No.: HY-N8521CAS No.: 950685-51-5
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Antileishmanial agent-16
0 ImagesCat. No.: HY-149957CAS No.: 2934738-41-5Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 µM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 µM). Antileishmanial agent-16 has good safety to mammalian cells (VERO cells).
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[10]-Shogaol (Standard)
![[10]-Shogaol (Standard)](https://file.medchemexpress.com/product_pic/hy-n2434r.gif "Click to View [10]-Shogaol (Standard) Product Detail")
0 ImagesCat. No.: HY-N2434RCAS No.: 36752-54-2-Shogaol (Standard) is the analytical standard of -Shogaol (HY-N2434). This product is intended for research and analytical applications. [10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC50 value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis.
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Diclazuril (Standard)
0 ImagesSynonyms: R-64433 (Standard)Diclazuril (Standard) is the analytical standard of Diclazuril. This product is intended for research and analytical applications. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
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Eugenitin
0 ImagesCat. No.: HY-W663230CAS No.: 480-12-6Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines.
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Cyclobendazole
0 ImagesCat. No.: HY-106585CAS No.: 31431-43-3Cyclobendazole is a benzimidazole derivative against protozoan parasites. Cyclobendazole shows in vitro activities against Trichomonas vaginalis (30236) and Giardia lamblia (wt), with IC50 values of 1.1 and 0.047 μg/mL, respectively.
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Antileishmanial agent-23
0 ImagesCat. No.: HY-155207CAS No.: 745033-86-7Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei.
