MK 436
MK 436 (MK-0436) is a metabolite with anti-trypanosomal activity that can be isolated from dog urine, particularly effective against Trypanosoma cruzi, the pathogen responsible for Chagas disease in South America.
For research use only. We do not sell to patients.
- CAS No.: 33450-08-7
- Formula: C11H14N4O3
- Molecular Weight:250.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 33450-08-7
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Molecular Weight 250.25
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Formula C11H14N4O3
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SMILES
O=[N+](C1=CN=C(C2=NOC3CCCCC23)N1C)[O-]
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Synonyms
MK-0436
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. VandenHeuvel, et al. Identification of canine urinary metabolites of the antiprotozoal agent 3a, 4, 5, 6, 7, 7a-hexahydro-3-(1-methyl-5-nitro-1H-imidazol-2-yl)-1, 2-benzisoxazole. Journal of pharmaceutical sciences 69.11 (1980): 1288-1292. [Content Brief]
[2]. Jennings, et al. Treatment with suramin and 2-substituted 5-nitroimidazoles of chronic murine Trypanosoma brucei infections with central nervous system involvement. Transactions of the Royal Society of Tropical Medicine and Hygiene 77.5 (1983): 693-698. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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