1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Phospholipase
  4. Phospholipase A Isoform
  5. Phospholipase A Inhibitor

Phospholipase A Inhibitor

Phospholipase A Inhibitors (21):

Cat. No. Product Name Effect Purity
  • HY-13402
    Varespladib
    Inhibitor 99.94%
    Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM.
  • HY-107411
    Bromoenol lactone
    Inhibitor 98.18%
    Bromoenol lactone ((6E)-Bromoenol lactone) is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β) with an IC50 value of approximately 7 μM, which inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.
  • HY-18570
    1-Naphthaleneacetic acid
    Inhibitor 99.89%
    1-Naphthaleneacetic acid (1-Naphthylacetic acid), a auxin, can promote plant growth.
  • HY-19757
    Lp-PLA2-IN-1
    Inhibitor 99.46%
    Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor.
  • HY-W012595A
    trans-Benzylideneacetone
    Inhibitor 99.29%
    trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2).
  • HY-120441
    CAY10590
    Inhibitor ≥98.0%
    CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases.
  • HY-116018
    FKGK11
    Inhibitor
    FKGK11 is a potent and selective inhibitor of GVIA iPLA2 (Group VIA calcium-independent phospholipase A2).
  • HY-116301
    CAY10502
    Inhibitor ≥99.0%
    CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme.
  • HY-108607
    PACOCF3
    Inhibitor ≥98.0%
    PACOCF3 (Palmityltrifluoromet​hylketone) is a selective phospholipase A2 inhibitor with an IC50 of 3.8 μM.
  • HY-N8213
    Rapanone
    Inhibitor 99.20%
    Rapanone is a natural benzoquinone.
  • HY-17485
    Alminoprofen
    Inhibitor 99.35%
    Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class.
  • HY-111376
    Pyrrophenone
    Inhibitor
    Pyrrophenone is a potent and specific cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 4.2 nM.
  • HY-13402A
    Varespladib sodium
    Inhibitor
    Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM.
  • HY-133148
    Lp-PLA2-IN-2
    Inhibitor
    Lp-PLA2-IN-2 is a potent and selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.
  • HY-11059
    sPLA2 inhibitor 1
    Inhibitor
    sPLA2 inhibitor 1, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa).
  • HY-108609
    YM-26734
    Inhibitor
    YM-26734 is a competitive inhibitor of secretory phospholipase A2 (PLA2) that exhibits a broad inhibitory profile to several PLA2s.
  • HY-101015A
    OBAA
    Inhibitor
    OBAA is a potent phospholipase A2 (PLA2) inhibitor with an IC50 of 70 nM.
  • HY-106555
    Protizinic acid
    Inhibitor
    Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity.
  • HY-101015
    (2E)-OBAA
    Inhibitor
    (2E)-OBAA is a potent phospholipase A2 (PLA2) inhibitor, with an IC50 of 70 nM.
  • HY-18570A
    1-Naphthaleneacetic acid potassium salt
    Inhibitor
    1-Naphthaleneacetic acid potassium salt (Potassium 1-Naphthaleneacetate), a synthetic auxin, can promote plant growth.