2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. RAD51
  5. RAD51 Degrader

RAD51 Degrader

RAD51 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-181651
    SZU305
    		Degrader
    SZU305 is a RAD51 PROTAC degrader, with DC50 values of 307.45 nM and 84.19 nM in SK-HEP-1 and Huh-7 cells, respectively. SZU305 inhibits DNA damage repair, induces cell cycle arrest and apoptosis. SZU305 moderately reduces the protein levels of IKZF1 and IKZF3 at high concentrations. SZU305 can be used in studies related to hepatocellular carcinoma.