Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards Related Products (11772)
Related Products (11772)
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Pregabalin lactam (Standard)
0 ImagesCat. No.: HY-W038877RCAS No.: 181289-23-6Synonyms: (S)-Pregabalin lactam (Standard)Pregabalin lactam (Standard) is an analytical standard for Pregabalin lactam. This product is used for research and analytical applications. Pregabalin lactam is a degradation product and is a common impurity with no mutagenicity.
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GSK-872 hydrochloride (Standard)
0 ImagesCat. No.: HY-101872ARCAS No.: 2703752-81-0GSK-872 hydrochloride (Standard) is the analytical standard of GSK-872 hydrochloride (HY-101872A). This product is intended for research and analytical applications. GSK-872 hydrochloride is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 hydrochloride decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury.
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Propacetamol hydrochloride (Standard)
0 ImagesPropacetamol (hydrochloride) (Standard) is the analytical standard of Propacetamol (hydrochloride). This product is intended for research and analytical applications. Propacetamol hydrochloride is a potent, peptidic inhibitor targeting thrombin and granzyme GZMK. Propacetamol hydrochloride specifically blocks the activities of thrombin and GZMK, thereby inhibiting thrombin-mediated PAR-1 cleavage, as well as downstream inflammatory and procoagulant signaling pathways. Through stabilizing IκB proteins, blocking NF-κB activation and reducing systemic levels of proinflammatory/procoagulant biomarkers, Propacetamol hydrochloride exerts multiple effects including anti-inflammatory, antithrombotic, barrier repair, and inhibition of atherosclerotic plaque progression. Propacetamol hydrochloride binds to platelets without interference from kininogen, effectively limiting acute thrombus growth and reducing eosinophil infiltration and goblet cell hyperplasia in asthma models. Propacetamol hydrochloride is an important tool molecule for investigating the mechanisms of atherosclerosis, asthma and related thromboinflammatory diseases.
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Cyclo(RGDyK) trifluoroacetate (Standard)
0 ImagesCyclo(RGDyK) (trifluoroacetate) (Standard) is the analytical standard of Cyclo(RGDyK) (trifluoroacetate) (HY-100563). This product is intended for research and analytical applications. Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
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Trifluralin (Standard)
0 ImagesTrifluralin (Standard) is the analytical standard of Trifluralin. This product is intended for research and analytical applications. Trifluralin is a selective, preemergence, soil-applied herbicide providing control of many important annual grass and broadleaf weed species. Trifluralin prevents weed growth by inhibiting root development through the interruption of mitosis. Trifluralin binds to tubulin and results in the failure of spindle apparatus and cell plate formation. Trifluralin inhibits radicle development on roots. Trifluralin inhibits cell mitosis. Trifluralin is considered to be neurotoxic and haematotoxic.
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UBP608 (Standard)
0 ImagesCat. No.: HY-100667RCAS No.: 2199-87-3
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2-Methoxycinnamic acid (Standard)
0 Images2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase.
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RS-25344 hydrochloride (Standard)
0 ImagesCat. No.: HY-108621RCAS No.: 152815-28-6RS-25344 hydrochloride (Standard) is the analytical standard of RS-25344 (hydrochloride) (HY-108621). This product is intended for research and analytical applications. RS-25344 hydrochloride is a selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC50 of 0.28 nM in human lymphocytes. RS-25344 hydrochloride has only weak inhibitory effects on PDE I, II, III (IC50 of >100 μM, 160 μM, 330 μM, respectively). RS-25344 hydrochloride has anti-inflammatory, memory- and cognition enhancing, and antineoplastic effects.
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Danoprevir (Standard)
0 ImagesCat. No.: HY-10238RCAS No.: 850876-88-9Synonyms: ITMN-191 (Standard); R7227 (Standard); RO5190591 (Standard); RG7227 (Standard)Danoprevir (Standard) is the analytical standard of Danoprevir (HY-10238). This product is intended for research and analytical applications. Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM). Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 μM.
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Azilsartan medoxomil (Standard)
0 ImagesSynonyms: TAK-491 (Standard)Azilsartan medoxomil (Standard) is the analytical standard of Azilsartan medoxomil (HY-14736). This product is intended for research and analytical applications. Azilsartan medoxomil (TAK 491), a prodrug form of Azilsartan (HY-14914), is an orally active angiotensin II receptor type 1 antagonist. Azilsartan medoxomil can be used for the study of essential hypertension.
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RIG-1 modulator 1 (Standard)
0 ImagesCat. No.: HY-107902RCAS No.: 1428729-63-8RIG-1 modulator 1 (Standard) is the analytical standard of RIG-1 modulator 1 (HY-107902). This product is intended for research and analytical applications. RIG-1 modulator 1 (Compound of claim 13) is an anti-viral compound which can be used against viral infections including influenza virus, HBV, HCV and HIV.
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3-Bromo-N,N-dimethyl-4-oxo-4-(P-tolyl)butanamide (Standard)
0 ImagesCat. No.: HY-W668514RCAS No.: 836627-56-63-Bromo-N,N-dimethyl-4-oxo-4-(P-tolyl)butanamide (Standard) is the analytical standard of 3-Bromo-N,N-dimethyl-4-oxo-4-(P-tolyl)butanamide. This product is intended for research and analytical applications.
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Binimetinib (Standard)
0 ImagesSynonyms: MEK162 (Standard); ARRY-162 (Standard); ARRY-438162 (Standard)Binimetinib (Standard) is the analytical standard of Binimetinib. This product is intended for research and analytical applications. Binimetinib (MEK162) is an oral and selective MEK1/2 inhibitor. Binimetinib (MEK162) inhibits MEK with an IC50 of 12 nM.
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Roquinimex (Standard)
0 ImagesSynonyms: Linomide (Standard); FCF89 (Standard); ABR212616 (Standard)Roquinimex (Standard) is the analytical standard of Roquinimex (HY-13743). Roquinimex (Linomide) is an orally active immunomodulator with antineoplastic, anti-inflammatory, and antiangiogenic activity. Roquinimex suppresses TH1 lymphocyte cytokines (IL-2, IFN-γ), promotes TH2 lymphocyte cytokines (IL-4, IL-10), increases NK cell, activated monocyte, and T cell activity. Roquinimex blocks macrophage TNF-α production and suppresses IL-1/IL-6 secretion. Roquinimex exhibits in vivo antitumour activity, suppresses rodent autoimmune disease signs, and ameliorates murine colitis and psoriasis. Roquinimex can be used for the research of leukemia, inflammatory bowel disease, multiple sclerosis, and psoriasis.
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Barlerin (Standard)
0 ImagesCat. No.: HY-N0758RCAS No.: 57420-46-9Synonyms: 8-O-Acetyl shanzhiside methyl ester (Standard)Barlerin (Standard) is the analytical standard of Barlerin. This product is intended for research and analytical applications. Barlerin (8-O-Acetyl shanzhiside methyl ester) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. Barlerin (8-O-Acetyl shanzhiside methyl ester) could inhibt NF-κB.
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Falnidamol (Standard)
0 ImagesSynonyms: BIBX 1382 (Standard)Falnidamol (Standard) is the analytical standard of Falnidamol. This product is intended for research and analytical applications. Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50>10 μM). Falnidamol is a pyrimido-pyrimidine compound and has anti-cancer activity.
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L-DABA (Standard)
0 ImagesSynonyms: L-2,4-Diaminobutyric acid (Standard)L-DABA (Standard) is the analytical standard of L-DABA. This product is intended for research and analytical applications. L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.
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PSB-0788 (Standard)
0 ImagesCat. No.: HY-103165RCAS No.: 1027513-54-7PSB-0788 (Standard) is the analytical standard of PSB-0788 (HY-103165). This product is intended for research and analytical applications. PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 can be used for the research for chronic inflammatory lung diseases.
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CDK8-IN-1 (Standard)
0 ImagesCat. No.: HY-103492RCAS No.: 1629633-48-2CDK8-IN-1 (Standard) is the analytical standard of CDK8-IN-1 (HY-103492). This product is intended for research and analytical applications. CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
