2. Anti-infection
  3. HBV HCV HIV Influenza Virus
  4. RIG-1 modulator 1

RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.

For research use only. We do not sell to patients.

RIG-1 modulator 1 Chemical Structure

RIG-1 modulator 1 Chemical Structure

CAS No. : 1428729-63-8

Size Price Stock Quantity
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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 110 In-stock
Solution
10 mM * 1 mL in DMSO USD 110 In-stock
Solid
5 mg USD 100 In-stock
10 mg USD 160 In-stock
25 mg USD 350 In-stock
50 mg USD 550 In-stock
100 mg USD 950 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1.

IC50 & Target

Influenza virus, HBV, HCV, HIV[1]
Molecular Weight

335.45

Formula

C14H17N5OS2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(NC1=NC2=CC=C(SC(C)=N3)C3=C2S1)NCCN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 35 mg/mL (104.34 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9811 mL 14.9053 mL 29.8107 mL
5 mM 0.5962 mL 2.9811 mL 5.9621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.54%

COA (248 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9811 mL 14.9054 mL 29.8107 mL 74.5268 mL
5 mM 0.5962 mL 2.9811 mL 5.9621 mL 14.9054 mL
10 mM 0.2981 mL 1.4905 mL 2.9811 mL 7.4527 mL
15 mM 0.1987 mL 0.9937 mL 1.9874 mL 4.9685 mL
20 mM 0.1491 mL 0.7453 mL 1.4905 mL 3.7263 mL
25 mM 0.1192 mL 0.5962 mL 1.1924 mL 2.9811 mL
30 mM 0.0994 mL 0.4968 mL 0.9937 mL 2.4842 mL
40 mM 0.0745 mL 0.3726 mL 0.7453 mL 1.8632 mL
50 mM 0.0596 mL 0.2981 mL 0.5962 mL 1.4905 mL
60 mM 0.0497 mL 0.2484 mL 0.4968 mL 1.2421 mL
80 mM 0.0373 mL 0.1863 mL 0.3726 mL 0.9316 mL
100 mM 0.0298 mL 0.1491 mL 0.2981 mL 0.7453 mL
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RIG-1 modulator 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIG-1 modulator 11428729-63-8HBVHCVHIVInfluenza VirusHepatitis B virusHepatitis C virusHuman immunodeficiency virusInhibitorinhibitorinhibit

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