2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. VEGFR
  5. VEGFR Degrader

VEGFR Degrader

VEGFR Isoform Comparison

VEGFR Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-160259
    VEGFR-2-IN-39
    		Degrader 99.09%
    VEGFR-2-IN-39 (PROTAC-5) is a PROTAC targeting VEGFR-2 (IC50: 208.6 nM). VEGFR-2-IN-39 has low toxicity.VEGFR-2-IN-39 inhibits the proliferation of EA.hy926, one of HUVECs, in a concentration-dependent manner, with an IC50 of 38.65 µM.
  • HY-146369
    PROTAC VEGFR-2 degrader-2
    		Degrader
    PROTAC VEGFR-2 degrader-2 is a VEGFR-2 (KDR) PROTAC degrader with weak inhibitory activity against VEGFR-2 (IC50 > 1 μM). It is applicable to the research of cancer-related pathological angiogenesis.