- Signaling Pathways
- Anti-infection
- Antibiotic
Antibiotic
Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.
Antibiotic Isoform Specific Products
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Antibiotic
(2774)
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Aminoglycoside
(46)
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Glycopeptide
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Lipopeptide
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Macrolide
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Oxazolidinone
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Quinolone
(101)
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Tetracycline
(42)
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β-lactam
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Antibiotic Related Products (3536)
Related Products (3536)
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Related Compound Screening Libraries (1)
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Antibiotic Isoform Comparison
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13-Hydroxyglucopiericidin A
0 ImagesCat. No.: HY-N15026CAS No.: 132150-13-113-Hydroxyglucopiericidin A is an antibiotic. 13-Hydroxyglucopiericidin A has strong anti-tumor cell activity. -
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β-Prumycin hydrochloride
0 ImagesCat. No.: HY-N14912CAS No.: 54612-74-7β-Prumycin hydrochloride is a carbohydrate antibiotic. β-Prumycin hydrochloride has anti-fungal activity and weak anti-individual bacterial activity. -
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Glycothiohexide α
0 ImagesCat. No.: HY-N15019CAS No.: 158446-31-2Glycothiohexide α is a peptide antibiotic. Glycothiohexide α has strong activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VREF), MIC values of 0.03-0.06 μg/mL. -
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Lenapenem
0 ImagesCat. No.: HY-105180CAS No.: 149951-16-6Synonyms: BO-2727 free acidLenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa. -
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10'-Desmethoxystreptonigrin
0 ImagesCat. No.: HY-137139CAS No.: 136803-89-910'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg). -
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Trimetrexate (Standard)
0 ImagesCat. No.: HY-10373RCAS No.: 52128-35-5Synonyms: CI-898 (Standard)Trimetrexate (Standard) is the analytical standard of Trimetrexate (HY-10373). This product is intended for research and analytical applications. Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer. -
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Dapsone (Standard)
0 ImagesSynonyms: 4,4′-Diaminodiphenyl sulfone (Standard); DDS (Standard)Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al. -
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Acetylstachyflin
0 ImagesCat. No.: HY-N14949CAS No.: 189185-59-9Acetylstachyflin is an antibiotic against influenza a virus. -
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Leucomycin A5
0 ImagesCat. No.: HY-125569CAS No.: 18361-45-0Leucomycin A5 has antifungal activity, with the MIC for Staphylococcus pyogenes pen S, Staphylococcus pyogenes pen R, and Staphylococcus faecalis being 0.8, 3.2, and 0.8 μg/mL, respectively. -
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Phenylpropiolic acid (Standard)
0 ImagesPhenylpropiolic acid (Standard) is the analytical standard of Phenylpropiolic acid (HY-W007319). This product is intended for research and analytical applications. Phenylpropiolic acid is an Antibacterial agent. Phenylpropiolic acid is identified from the intracellular extract of Proteus mirabilis DMTMMR-11. Phenylpropiolic acid disrupts biofilm formation by reducing pathogen adhesion and enhancing biofilm clearance ability. Phenylpropiolic acid inhibits the growth of Yersinia enterocolitica, disrupts its cell membrane integrity, and increases the survival rate of infected Caenorhabditis elegans. Phenylpropiolic acid can be used in studies related to yersiniosis and gastroenteritis. -
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Albiducin A
0 ImagesCat. No.: HY-N15343CAS No.: 2222286-14-6Albiducin A is an antibiotic found in Hymenoscyphus albidus, exhibiting antibacterial and anticancer activities. The MIC range of Albiducin A against bacteria and fungi is 16.7-66.7 mg/mL. Its IC50 values for mouse fibroblast cell line (L929) and human cervical carcinoma cell line (KB3-1) are 6.1 and 2.7 μg/mL, respectively. Albiducin A holds promise for research in the fields of infection and cancer diseases. -
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Napyradiomycin B2
0 ImagesCat. No.: HY-N14804CAS No.: 103106-21-4Napyradiomycin B2 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B2 almost none to Gram-negative bacteria and fungi. -
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Saptomycin E
0 ImagesCat. No.: HY-124262CAS No.: 137714-92-2Saptomycin E is an antitumor antibiotic. -
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Sannamycin G
0 ImagesCat. No.: HY-123339CAS No.: 73522-72-2Synonyms: Istamycin X0; IST-X0Sannamycin G (Istamycin X0) is an aminoglycoside antibiotic and has only weak antibacterial activity against a few bacteria. -
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Parvodicin C4
0 ImagesCat. No.: HY-N15040CAS No.: 110882-87-6Parvodicin C4 is a glycopeptide antibiotic. Parvodicin C4 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis. -
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Sulfanilamide (Standard)
0 ImagesSulfanilamide (Standard) is the analytical standard of Sulfanilamide. This product is intended for research and analytical applications. ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum. -
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11-Deoxy-13-dihydrodaunorubicin
0 ImagesCat. No.: HY-N15106CAS No.: 71800-90-311-Deoxy-13-deoxodaunorubicin is an anthracycline antibiotic with anti-Gram-positive bacteria, negative bacteria and tumor activity. -
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Succinylsulfathiazole (Standard)
0 ImagesSuccinylsulfathiazole (Standard) (Succinylsulphathiazole) is the analytical standard of Succinylsulfathiazole (HY-B0921). This product is intended for research and analytical applications. Succinylsulfathiazole is a long-acting sulfonamide antibiotic with localized gut-specific antibacterial activity and is orally active. Succinylsulfathiazole inhibits bacterial folate synthesis, reduces coliform counts, suppresses intestinal bacterial growth and vitamin biosynthesis, and depletes gut folate-producing bacteria. Succinylsulfathiazole modulates hepatic mTOR signaling, diminishes cecal fermentation, decreases hepatic folate levels and total folate excretion, elevates nitrogen excretion and reduces the fermentability of certain dietary fibers. Succinylsulfathiazole induces folate deficiency and triggers biotin- and folate-related nutritional deficiency symptoms in rats and C57BL/6 mice. -
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Miyakamide A2
0 ImagesCat. No.: HY-N14275CAS No.: 497252-39-8Miyakamide A2 is an antibiotic with insecticidal effect. Miyakamide A2 inhibits the growth of Artemia salina. Miyakamide A2 has a weak antixanthomonas activity. Miyakamide A2 inhibits P388 cells with an IC50 of 12.2 μg/mL. -
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Deoxyfrenolicin
0 ImagesCat. No.: HY-N14134CAS No.: 10023-11-7Deoxyfrenolicin is a quinone antibiotic that can be isolated from the fermentation broth of the Streptomyces roseofulvus strain AM-3867. Deoxyfrenolicin belongs to the frenolicin class of antibiotics. Deoxyfrenolicin exhibits antibacterial activity in vitro and can effectively inhibit the activity of Mycoplasma gallisepticum. -
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