1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-109755
    PF-04064900
    PF-04064900 is a prodrug of sulopenem penem antibiotic.
    PF-04064900
  • HY-B0688S3
    Dapsone-15N2
    Dapsone-15N2 (4,4′-Diaminodiphenyl sulfone-15N2) is 15N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
    Dapsone-<sup>15</sup>N<sub>2</sub>
  • HY-N14913
    Adenomycin
    Adenomycin is an antibiotic that is effective against a wide range of mycobacteria.
    Adenomycin
  • HY-N15024
    Eupenoxide
    Eupenoxide is an antibiotic with antifungal activity that can be found by fungi of the genus Eupenicillium.
    Eupenoxide
  • HY-N14303
    16-Methyloxazolomycin
    16-Methyloxazolomycin is an antibiotic. 16-Methyloxazolomycin has the effect of resisting bacteria and algae. 16-Methyloxazolomycin against leukemia P388 and human lung adenocarcinoma cells.
    16-Methyloxazolomycin
  • HY-N14296
    Fluvirucin B1
    Fluvirucin B1 is an antibiotic against influenza A virus.
    Fluvirucin B1
  • HY-B0510S3
    Trimethoprim-13C3
    Trimethoprim-13C3 is the deuterium labeled Trimethoprim (HY-B0510). Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc.
    Trimethoprim-<sup>13</sup>C<sub>3</sub>
  • HY-101479S
    Iclaprim-d6
    Iclaprim-d6 (AR-100-d6) is the deuterium labeled Iclaprim. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
    Iclaprim-d<sub>6</sub>
  • HY-B0643R
    Dirithromycin (Standard)
    Dirithromycin (Standard) is the analytical standard of Dirithromycin. This product is intended for research and analytical applications. Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis.
    Dirithromycin (Standard)
  • HY-N15032
    Espinomycin A3
    Espinomycin A3 is a sixteen-membered macrolide antibiotic. Espinomycin A3 is active against Gram-positive bacteria.
    Espinomycin A3
  • HY-B1046R
    Clofazimine (Standard)
    Clofazimine (Standard) is the analytical standard of Clofazimine. This product is intended for research and analytical applications. Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC50 = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research.
    Clofazimine (Standard)
  • HY-N15026
    13-Hydroxyglucopiericidin A
    13-Hydroxyglucopiericidin A is an antibiotic. 13-Hydroxyglucopiericidin A has strong anti-tumor cell activity.
    13-Hydroxyglucopiericidin A
  • HY-N14912
    β-Prumycin hydrochloride
    β-Prumycin hydrochloride is a carbohydrate antibiotic. β-Prumycin hydrochloride has anti-fungal activity and weak anti-individual bacterial activity.
    β-Prumycin hydrochloride
  • HY-N15019
    Glycothiohexide α
    Glycothiohexide α is a peptide antibiotic. Glycothiohexide α has strong activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VREF), MIC values of 0.03-0.06 μg/mL.
    Glycothiohexide α
  • HY-105180
    Lenapenem
    Lenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa.
    Lenapenem
  • HY-137139
    10'-Desmethoxystreptonigrin
    10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg).
    10'-Desmethoxystreptonigrin
  • HY-10373R
    Trimetrexate (Standard)
    Trimetrexate (Standard) is the analytical standard of Trimetrexate (HY-10373). This product is intended for research and analytical applications. Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.
    Trimetrexate (Standard)
  • HY-B0688R
    Dapsone (Standard)
    Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
    Dapsone (Standard)
  • HY-N14949
    Acetylstachyflin
    Acetylstachyflin is an antibiotic against influenza a virus.
    Acetylstachyflin
  • HY-125569
    Leucomycin A5
    Leucomycin A5 has antifungal activity, with the MIC for Staphylococcus pyogenes pen S, Staphylococcus pyogenes pen R, and Staphylococcus faecalis being 0.8, 3.2, and 0.8 μg/mL, respectively.
    Leucomycin A5

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