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Referencia número: HY-137139

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10'-Desmethoxystreptonigrin

10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC₅₀ of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD₅₀ is 8.8 mg/kg).

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No. CAS: 136803-89-9
Fòrmula: C₂₄H₂₀N₄O₇
Peso molecular:476.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

10'-Desmethoxystreptonigrin Chemical Structure

No. CAS: 136803-89-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Descripciòn
- IC₅₀ & Target
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IC₅₀ & Target

IC₅₀: 21 μM (Ras Farnesyltransferase)

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Chemical Information

No. CAS 136803-89-9
Peso molecular 476.44
Fòrmula C₂₄H₂₀N₄O₇
SMILES

NC(C(C(C=CC=C1OC)=C1O)=C2C)=C(C3=CC=C(C4=O)C(C(C(N)=C4OC)=O)=N3)N=C2C(O)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces albus
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Liu WC, et al. 10'-Desmethoxystreptonigrin, a novel analog of streptonigrin. J Antibiot (Tokyo). 1992 Apr;45(4):454-7. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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10'-Desmethoxystreptonigrin

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10'-Desmethoxystreptonigrin

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