2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17591
    9-Hydroxy-10E,12Z-octadecadienoic acid methyl ester
    9-Hydroxy-10E,12Z-octadecadienoic acid methyl ester is a natural product that can be found in safflower.
    9-Hydroxy-10E,12Z-octadecadienoic acid methyl ester
  • HY-106849
    Y-26611
    Y-26611 is an orally active new type of quinolone derivative. Y-26611 exhibits strong phototoxicity under UV irradiation and can significantly induce lipid peroxidation of human red blood cell membrane.
    Y-26611
  • HY-N19779
    Scropolioside D
    Scropolioside D (Scrospioside A; Scropheanoside III) is an orally active acylated iridoid glycoside found in the roots of Scrophularia saharae with antidiabetic activity.
    Scropolioside D
  • HY-N16873
    Pseudoginsenoside RP1
    Pseudoginsenoside RP1 is a natural triterpene.
    Pseudoginsenoside RP1
  • HY-129672
    Thelenotoside B
    Thelenotoside B (25-Dihydrostichorrenoside E) shows strong cytotoxicities against five cancer cell lines as HepG2, KB, LNCaP, MCF7 and SK-Mel2 with the IC50 values from 0.95 ± 0.08 to 1.90 ± 0.13 μM. Thelenotoside B is a triterpene tetraglycoside.
    Thelenotoside B
  • HY-171715
    PL-13
    PL-13 (Compound P11) is the derivative of Trabectedin. PL-13 can disrupt the function of DNA and induces apoptosis in cancer cells. PL-13 be can be used for the research of cancer.
    PL-13
  • HY-119140
    LY 116467
    LY 116467 is an active compound.
    LY 116467
  • HY-155039
    Antitumor agent-105
    Antitumor agent-105 (Compound 37) is an antitumor agent. Antitumor agent-105 has antitumor activity against A549, H1299, H460, HCT116, MDA-MB-231 cells, with IC50 values of 6.7, 8.3, 4.3, 4.4, 6.7 μM respectively.
    Antitumor agent-105
  • HY-49075
    WAY-622252
    		98.0%
    WAY-622252 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-622252
  • HY-N17870
    Epimedoicarisoside A
    Epimedoicarisoside A is a 9,10-dihydrophenanthrene derivative found in the aerial parts of Epimedium koreanum.
    Epimedoicarisoside A
  • HY-129513
    SIB-1893
    SIB-1893 is an active compound.
    SIB-1893
  • HY-118464
    AC915
    AC915 is an active compound.
    AC915
  • HY-184348
    PhenDC3n-az
    PhenDC3n-az is the azide (-N3) derivative of PhenDC3 (HY-15594), and it is mainly used for click chemistry-based G-quadruplex binding protein pull-down or in situ labeling studies.
    PhenDC3n-az
  • HY-49458
    WAY-232897
    		98.0%
    WAY-232897 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-232897
  • HY-N12302A
    (E/Z)-Scotanamine D
    (E/Z)-Scotanamine D is a hydroxycinnamic acid amide found in the roots of Scopolia tangutica. (E/Z)-Scotanamine D is inactive against μ-, δ-, and κ-opioid receptors.
    (E/Z)-Scotanamine D
  • HY-W746269
    KCA 098
    KCA 098 is an orally active benzofuroquinoline derivative. KCA 098 can inhibit bone resorption and stimulat bone formation of chick embryo. KCA 098 can increase calcium and phosphorus content as well as the amount of force required to break the femur from ovariectomized rats. KCA 098 can be used for the research of bone diseases.
    KCA 098
  • HY-175085
    17-Phenyl trinor 8-iso prostaglandin E2
    17-Phenyl trinor 8-iso prostaglandin E2 is a prostaglandin analog that reduces intraocular pressure (IOP) in both normal and glaucomatous monkey eyes. 17-Phenyl trinor 8-iso prostaglandin E2 lowers IOP primarily by increasing trabecular outflow facility.
    17-Phenyl trinor 8-iso prostaglandin E2
  • HY-N19879
    Obliquetin
    Obliquetin is a coumarin derivative of aesculetin and 6-monomethyl ether of obliquetol, found in the heartwood of Ptaeroxylon obliquum.
    Obliquetin
  • HY-N11740
    4-O-Methylolivetolcarboxylic acid
    4-O-Methylolivetolcarboxylic acid is an olivetolcarboxylic acid derivative that can be found in the lichen Cladonia stellaris, belonging to the category of secondary metabolites.
    4-O-Methylolivetolcarboxylic acid
  • HY-N18041
    Pseudostellarin E
    Pseudostellarin E is a proline-rich, caryophyllaceous cyclopeptide present in the roots of Pseudostellaria heterophylla. Pseudostellarin E can be synthesized by overexpressing its precursor gene prePhPE in the leaves of Nicotiana benthamiana.
    Pseudostellarin E