Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11091)
Related Products (11091)
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Loxapine impurity 2-d8
0 ImagesCat. No.: HY-143975SLoxapine impurity 2-d8 is the deuterium labeled Loxapine impurity 2.
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Propane-1,2,3-triyl tripalmitate-13C3-1
0 ImagesCat. No.: HY-W013061S4CAS No.: 201996-42-1Propane-1,2,3-triyl tripalmitate-13C3-1 is the 13C labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).
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Beclomethasone 17-Propionate-d5
0 ImagesCat. No.: HY-W654066Beclomethasone 17-Propionate-d5 is deuterated labeled Beclomethasone 17-Propionate.
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Nemonoxacin-13C,d3 dihydrochloride
0 ImagesCat. No.: HY-14956S4Synonyms: TG-873870-13C,d3 dihydrochlorideNemonoxacin-13C,d3 dihydrochloride (TG-873870-13C,d3 dihydrochloride) is the deuterium and 13C-labeled Nemonoxacin dihydrochloride. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia.
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(Z)-4-(Methoxy-d3)-4-oxobut-2-enoic acid
0 ImagesCat. No.: HY-W705769CAS No.: 1266402-66-7(Z)-4-(Methoxy-d3)-4-oxobut-2-enoic acid is the deuterium labeled Monomethyl maleate (HY-W129396).
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Nivalenol-13C15
0 ImagesCat. No.: HY-N6801SCAS No.: 911392-40-0Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801). Nivalenol, a trichothecene mycotoxin that can be produced by Fusarium graminearum, is a fungal metabolite present in agricultural product. Nivalenol modulates apoptotic pathway, cell cycle regulation, Bax, ERK, caspase-3, and poly-ADP-ribose synthase activity in macrophages. Nivalenol inhibits ribosomal peptidyltransferase site, protein synthesis, DNA synthesis, and cell proliferation. Nivalenol induces late-stage apoptotic morphological changes, reduces cellular metabolism, and decreases cell proliferation in erythroleukemia cells. Nivalenol induces lymphocyte apoptosis in murine thymus, spleen, and Peyer's patches. Nivalenol can be used for the research of erythroleukemia.
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N-Tridecanoyl-D-erythro-sphinganine-d7
0 ImagesCat. No.: HY-146763SCAS No.: 2315262-21-4N-Tridecanoyl-D-erythro-sphinganine-d7 is deuterium labeled N-Tridecanoyl-D-erythro-sphinganine.
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2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5
0 ImagesCat. No.: HY-W339957SCAS No.: 1276197-38-62,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2,6-Dichloro-1,1'-biphenyl.
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Rosuvastatin-d3
0 ImagesCat. No.: HY-17504ASCAS No.: 1133429-16-9Synonyms: ZD 4522 d3Rosuvastatin-d3 is the deuterated-labeled Rosuvastatin (HY-17504A). Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
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Boc-Glycine-13C,15N
0 ImagesCat. No.: HY-Y0978S4CAS No.: 145143-01-7Synonyms: N-tert-Butoxycarbonyl-2-aminoacetic acid-13C,15N; NSC 127669-13C,15NBoc-Glycine-13C,15N (N-tert-Butoxycarbonyl-2-aminoacetic acid-13C,15N) is the 13C- and 15N-labeled Boc-Glycine (HY-Y0978). Boc-Glycine is a Glycine (HY-Y0966) derivative.
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Deltamethrin-d5
0 ImagesCat. No.: HY-B1971SCAS No.: 2140301-99-9Synonyms: Decamethrin-d5Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.
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trans-Trismethoxy Resveratrol-d4
0 ImagesCat. No.: HY-W034097SCAS No.: 1089051-64-8trans-Trismethoxy Resveratrol-d4 is the deuterium labeled trans-Trismethoxy Resveratrol.
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Acetylcysteine-15N
0 ImagesCat. No.: HY-B0215S1Synonyms: N-Acetylcysteine-15N; N-Acetyl-L-cysteine-15N; NAC-15NAcetylcysteine-15N (N-Acetylcysteine-15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies.
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Topiroxostat-d4
0 ImagesCat. No.: HY-14874SCAS No.: 2732868-49-2Synonyms: FYX-051-d4Topiroxostat-d4 is deuterium labeled Topiroxostat. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment.
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Octocrylene-13C3
0 ImagesCat. No.: HY-W654296Octocrylene-13C3 is the 13C-labeled Octocrylene (HY-A0087). Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes.
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Dacomitinib-d10
0 ImagesCat. No.: HY-13272S3Synonyms: PF-00299804-d10; PF-299804-d10
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3-(Methylthio)propylamine-d3
0 ImagesCat. No.: HY-W142881SSynonyms: Methylmercaptopropylamine-d33-(Methylthio)propylamine-d3 (Methylmercaptopropylamine-d3) is the deuterium labeled 3-(Methylthio)propylamine.
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p-Azoxyanisole-d6
0 ImagesCat. No.: HY-W283596SCAS No.: 34172-21-9p-Azoxyanisole-d6 is the deuterium labeled p-Azoxyanisole.
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Cimaterol-d7
0 ImagesSynonyms: CL 263780-d7Cimaterol-d7 is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.
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16α-Hydroxyprednisolone-d5
0 ImagesCat. No.: HY-117580S2Synonyms: OH-PRED-d516α-Hydroxyprednisolone-d5 (OH-PRED-d5) is the deuterium labeled 16α-Hydroxyprednisolone (HY-117580). 16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily.
