Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11128)
Related Products (11128)
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Rucaparib-d3
0 ImagesSynonyms: AG014699-d3; PF-01367338-d3Rucaparib-d3 (AG014699-d3) is the deuterated -labeled Rucaparib (HY-10617A). Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research.
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(2R)-Sorbitan Monolauric Acid Ester-d22
0 ImagesCat. No.: HY-W707578(2R)-Sorbitan Monolauric Acid Ester-d22-1 is the deuterium labeled (2R)-Sorbitan Monolauric Acid Ester.
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6-Desamino 6-chloro etravirine-13C3
0 ImagesCat. No.: HY-W777751CAS No.: 1246818-40-56-Desamino 6-chloro etravirine-13C3 is the 13C-labeled 6-Desamino 6-Chloro Etravirine (HY-W740641).
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d31
0 ImagesCat. No.: HY-141617S11-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d31 is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE (HY-141617). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control.
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DL-Methionine-13C
0 ImagesCat. No.: HY-N0325SCAS No.: 68799-90-6DL-Methionine-13C is the 13C-labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants.
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Sanguinarine chloride-13C,d3
0 ImagesCat. No.: HY-W768895Synonyms: Sanguinarin chloride-13C,d3; Sanguinarium chloride-13C,d3; Pseudochelerythrine chloride-13C,d3Sanguinarine chloride-13C,d3 (Sanguinarin chloride-13C,d3) is the deuterium labeled Sanguinarine chloride (HY-N0052A). Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
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Taurolithocholic acid-d5
0 ImagesCat. No.: HY-113308SCAS No.: 1265681-64-8Taurolithocholic acid-d5 is deuterium labeled Taurolithocholic acid. Taurolithocholic acid is an orally active bile acid and antiviral agent. Taurolithocholic acid upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis, viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic acid also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic acid serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic acid shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic acid not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis.
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Pretomanid-d5
0 ImagesCat. No.: HY-10844S1Synonyms: PA-824-d5; (S)-PA 824-d5Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
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SN-38-13C6
0 ImagesCat. No.: HY-13704S2CAS No.: 718612-55-6Synonyms: 7-Ethyl-10-hydroxycamptothecin-13C6SN-38-13C6 (7-Ethyl-10-hydroxycamptothecin-13C6) is the 13C-labeled SN-38 (HY-13704). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254).
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Diethyl phthalate-d10
0 ImagesCat. No.: HY-Y0284S1CAS No.: 1817006-92-0Diethyl phthalate-d10 is the d10 labeled Diethyl phthalate (HY-Y0284). Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility.
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4-Hydroxychlorpropham-d7
0 ImagesCat. No.: HY-W714025S4-Hydroxychlorpropham-d7 is the deuterium labeled Isopropyl (3-chloro-4-hydroxyphenyl)carbamate (HY-W714025).
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L-Prolinamide-d3
0 ImagesCat. No.: HY-20582SCAS No.: 1276197-55-7L-Prolinamide-d3 is the deuterium labeled L-Prolinamide[1]. L-Prolinamide is a proline derivative[2].
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1,3-Dimyristoyl-glycerol-d5
0 ImagesCat. No.: HY-W127588SCAS No.: 1246523-63-61,3-Dimyristoyl-glycerol-d5 is deuterium labeled 1,3-Dimyristoyl-glycerol.
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1,4-Diiodobutane-13C4
0 ImagesCat. No.: HY-W771025CAS No.: 2731163-22-5Synonyms: Tetramethylene Iodide (stabilized with Copper chip)-13C41,4-Diiodobutane-13C4 (Tetramethylene Iodide (stabilized with Copper chip)-13C4) is the 13C-labeled 1,4-Diiodobutane (HY-W004871).
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(-)-Fucose-13C-3
0 ImagesCat. No.: HY-N1480S3CAS No.: 478518-51-3Synonyms: 6-Desoxygalactose-13C-3; L-(-)-Fucose-13C-3; L-Galactomethylose-13C-3(-)-Fucose-13C-3 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
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2-Morpholinoethanol-d4
0 ImagesCat. No.: HY-W010387SCAS No.: 1185052-90-72-Morpholinoethanol-d4 is the deuterium labeled 2-Morpholinoethanol.
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NSC 30973-13C
0 ImagesCat. No.: HY-W778773CAS No.: 1391054-60-6NSC 30973-13C is the 13C-labeled
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Flavoxate-d5
0 ImagesCat. No.: HY-B0549SCAS No.: 2748541-85-5Flavoxate-d5 is deuterium labeled Flavoxate. Flavoxate hydrochloride (Rec-7-0040; DW61) is an orally active L-type Ca2+ channel inhibitor and antispasmodic. Flavoxate hydrochloride inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba2+ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors. Consequently, Flavoxate hydrochloride induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate hydrochloride effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate hydrochloride can be used in research on overactive bladder and related voiding dysfunctions.
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1-Palmitoyl-2-linoleoyl-rac-glycerol-d5
0 ImagesCat. No.: HY-W7702041-Palmitoyl-2-linoleoyl-rac-glycerol-d5 is the deuterium labeled 1-Palmitoyl-2-linoleoyl-rac-glycerol (HY-W740434). 1-Palmitoyl-2-linoleoyl-rac-glycerol is a diacylglycerol that contains Palmitic acid (HY-N0830).
