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Cat. No.: HY-W768895

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Sanguinarine chloride-¹³C,d₃

Name: Sanguinarine chloride-13C,d3
Brand: MedChemExpress
SKU: HY-W768895
Availability: PreOrder

(Synonyms: Sanguinarin chloride-13C,d3; Sanguinarium chloride-13C,d3; Pseudochelerythrine chloride-13C,d3)

Sanguinarine chloride-¹³C,d₃ (Sanguinarin chloride-¹³C,d₃) is the deuterium labeled Sanguinarine chloride (HY-N0052A). Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

For research use only. We do not sell to patients.

Formula: C₁₉¹³CH₁₁D₃ClNO₄
Molecular Weight:371.79

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Sanguinarine chloride-¹³C,d₃ Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

All Parasite Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 5578-73-4
Molecular Weight 371.79
Formula C₁₉¹³CH₁₁D₃ClNO₄
SMILES

[2H][13C]([2H])([N+]1=CC2=C(C3=C1C4=CC5=C(C=C4C=C3)OCO5)C=CC6=C2OCO6)[2H].[Cl-]
Synonyms

Sanguinarin chloride-13C,d3; Sanguinarium chloride-13C,d3; Pseudochelerythrine chloride-13C,d3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang Y, Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species. Oncotarget. 2016 Apr 19;7(16):22355-67. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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Sanguinarine chloride-13C,d3

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Sanguinarine chloride-13C,d3 Related Classifications

HY-W768895 Related Classifications

Bioz

Sanguinarine chloride-¹³C,d₃

Sanguinarine chloride-¹³C,d₃ Related Classifications