mAChR
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mAChR Related Products (484)
Related Products (484)
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(S)-Vamicamide
0 ImagesCat. No.: HY-U00079BCAS No.: 151851-72-8Synonyms: (S)-FK-176(S)-Vamicamide ((S)-FK-176) is an anticholinergic compound.
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Succinylcholine iodide
0 ImagesSuccinylcholine iodide (Suxamethonium iodide) is a depolarizing neuromuscular blocker with rapid onset and short duration of action. Succinylcholine iodide also acts as an agonist of the Acetylcholine receptor. Succinylcholine iodide is used for emergency airway management.
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Darifenacin-d4
0 ImagesCat. No.: HY-A0033S1CAS No.: 1095598-84-7Synonyms: UK-88525-d4Darifenacin-d4 is the deuterium labeled Darifenacin. Darifenacin(UK88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9. IC50 value: 8.9 (pKi).
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Darenzepine
0 ImagesCat. No.: HY-100154CAS No.: 84629-61-8Darenzepine is a muscarinic receptor inhibitor extracted from patent US 20170095465 A1.
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Pirenzepine-d8 dihydrochloride
0 ImagesCat. No.: HY-17037S1CAS No.: 2982740-97-4Synonyms: LS 519-d8 dihydrochloride; Pirenzepin-d8 dihydrochloride; Gastrozepin-d8 dihydrochloridePirenzepine-d8 (LS 519-d8; Pirenzepin-d8) dihydrochloride is a deuterium labeled Pirenzepine (dihydrochloride) (HY-17037). Pirenzepine (LS 519) dihydrochloride is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine dihydrochloride reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine dihydrochloride shows anti-proliferative activity to cancer cells.
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M1/M4 muscarinic agonist 3
0 ImagesCat. No.: HY-149732CAS No.: 2640109-30-2M1/M4 muscarinic agonist 3 (compound 44) is a muscarinic mAChR M1/M4 agonist with EC50s of 31 nM and 9.3 nM, respectively.
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β2AR agonist 7
0 ImagesCat. No.: HY-184681CAS No.: 3109318-09-1β2AR agonist 7 is a MABA with both muscarinic acetylcholine M3 receptor antagonistic activity and β2-adrenergic receptor agonistic activity, with a Ki of 1.75 nM for hM3 and an EC50 of 0.054 nM for hβ2. β2AR agonist 7 binds to the M3 muscarinic receptor with high affinity and long-acting kinetic characteristics. β2AR agonist 7 induces smooth muscle relaxation and acts as a bronchoprotective agent against acute bronchoconstriction. β2AR agonist 7 can be used in the research of asthma and chronic obstructive pulmonary disease.
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Vamicamide
0 ImagesCat. No.: HY-U00079ACAS No.: 132373-81-0Synonyms: FK-176Vamicamide (FK-176) is an orally active competitive mAChR antagonist that inhibits contractions induced by cholinergic nerve stimulation by preventing mAChR agonists from binding to mAChR. Vamicamide exhibits a good anti-bladder spasm effect, with a pA2 value of 6.82 in bladder tissue. Vamicamide can be used in research within the field of neurological diseases.
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AZD-9164 bromide
0 ImagesCat. No.: HY-113692CAS No.: 1034916-72-7AZD-9164 (bromide) is a long-acting muscarinic M3 antagonist. AZD-9164 (bromide) is promising for research of airways diseases, such as chronic obstructive pulmonary disease (COPD) or asthma.
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(Rac)-Tolterodine-d5
0 ImagesCat. No.: HY-A0024AS1CAS No.: 2747918-62-1(Rac)-Tolterodine-d5 is deuterium labeled (rac)-Tolterodine.
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L-(-)-Neopterin
0 ImagesCat. No.: HY-W040055ACAS No.: 2277-43-2Synonyms: L-erythro-NeopterinL-(-)-Neopterin (L-erythro-Neopterin) is a cholinergic receptor that acts as a competitive antagonist, countering the inhibitory effects of pteridine diuretics on the growth of Crithidia fasciculata. L-(-)-Neopterin can be used in research related to the nervous system and purine metabolism.
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Ethybenztropine hydrobromide
0 ImagesCat. No.: HY-118406BCAS No.: 24815-25-6Synonyms: Ponalid hydrobromide; UK 738 hydrobromideEthybenztropine hydrobromide (Ponalid hydrobromide) is an anticholinergic drug with antiparkinsonian activity. Ethybenztropine hydrobromide may also act as a dopamine reuptake inhibitor. Ethybenztropine hydrobromide is commonly used to suppress Parkinson's disease.
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(Rac)-Sabcomeline
0 ImagesCat. No.: HY-167947CAS No.: 149156-36-5Synonyms: (Rac)-SB-202026; (Rac)-Memric(Rac)-Sabcomeline ((Rac)-SB-202026) serves as an M1/M4 muscarinic agonist, making it a valuable tool in the exploration of neurological disorders, including schizophrenia.
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Muscarinic M3 receptor antagonist-2
0 ImagesCat. No.: HY-177310CAS No.: 886490-86-4Muscarinic M3 receptor antagonist-2 (Compound 30) is a muscarinic M3 receptor antagonist.
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Fesoterodine fumarate (Standard)
0 ImagesFesoterodine (fumarate) (Standard) is the analytical standard of Fesoterodine (fumarate). This product is intended for research and analytical applications. Fesoterodine Fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine Fumarate is used for the overactive bladder (OAB).
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Terodiline
0 ImagesTerodiline, an antispasmodic agent, blocks hERG current with the IC50 of 375 nM. Terodiline has both anticholinergic and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability. Terodiline can be used for the research of urinary incontinence.
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L-Hyoscyamine sulfate (Standard)
0 ImagesCat. No.: HY-N0471ARCAS No.: 620-61-1Synonyms: Daturine sulfate (Standard)L-Hyoscyamine (sulfate) (Standard) is the analytical standard of L-Hyoscyamine (sulfate). This product is intended for research and analytical applications. L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate is a levo-isomer to Atropine (HY-B1205).
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Dihexyverine hydrochloride
0 ImagesDihexyverine hydrochloride is a compound belonging to the amino alcohol ester class. Dihexyverine hydrochloride possesses anticholinergic, smooth muscle relaxant, antihistaminic, and antiemetic effects. Dihexyverine hydrochloride can also shorten the duration of labor. Dihexyverine hydrochloride can be used in research related to gastrointestinal spasms, obstetrics, and other fields.
