2. Signaling Pathways
  3. Others
  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (10970):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0679R
    Lubiprostone (Standard)
    Lubiprostone (Standard) is the analytical standard of Lubiprostone. This product is intended for research and analytical applications. Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research.
    Lubiprostone (Standard)
  • HY-B1343R
    Pridinol mesylate (Standard)
    Pridinol mesylate (Standard) is the analytical standard of Pridinol mesylate (HY-B1343). This product is intended for research and analytical applications. Pridinol mesylate is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. Pridinol mesylate reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol mesylate inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases.
    Pridinol mesylate (Standard)
  • HY-45169R
    Exatecan intermediate 13 (Standard)
    Ethyl 2-(6-(acetamidomethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate (Standard) is the analytical standard of Ethyl 2-(6-(acetamidomethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate. This product is intended for research and analytical applications.
    Exatecan intermediate 13 (Standard)
  • HY-100037R
    NT157 (Standard)
    NT157 (Standard) is the analytical standard of NT157 (HY-100037). This product is intended for research and analytical applications. NT157 (Tyrphostin NT157) is a selective IRS-1/2 inhibitor that induces Ser-phosphorylation and consequently the degradation of IRS-1/2. NT157 (Tyrphostin NT157) is a first-in-class anti-cancer agent that also targets Stat3 signaling pathway.
    NT157 (Standard)
  • HY-A0236AR
    Aprindine hydrochloride (Standard)
    Aprindine hydrochloride (Standard) is the analytical reference standard of Aprindine hydrochloride (HY-A0236A). This product is used for research and analytical applications. Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. Aprindine hydrochloride mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine hydrochloride significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine hydrochloride can also regulate intracellular calcium ion concentration by inhibiting Na+/Ca2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine hydrochloride can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias.
    Aprindine hydrochloride (Standard)
  • HY-W014069R
    11-Mercaptoundecanoic acid (Standard)
    11-Mercaptoundecanoic acid (Standard) is an analytical standard of 11-Mercaptoundecanoic acid (HY-W014069R). This product is used for research and analytical applications. 11-Mercaptoundecanoic acid is a self-assembled monolayer membrane composed of long-chain alkane chains and carboxyl-containing thioalcohols and can be used as a metal surface modifier. 11-Mercaptoundecanoic acid is widely applied in the research of molecular probes, self-assembled membranes, nanomaterials, and biological materials, etc.
    11-Mercaptoundecanoic acid (Standard)
  • HY-100531R
    DprE1-IN-2 (Standard)
    DprE1-IN-2 (Standard) is the analytical standard of DprE1-IN-2 (HY-100531). This product is intended for research and analytical applications. DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect.
    DprE1-IN-2 (Standard)
  • HY-13215R
    Avasimibe (Standard)
    Avasimibe (Standard) is the analytical standard of Avasimibe. This product is intended for research and analytical applications. Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively. Avasimibe can be used for the research of prostate cancer.
    Avasimibe (Standard)
  • HY-129040AR
    m-Iodobenzylguanidine sulfate (Standard)
    m-Iodobenzylguanidine (sulfate) (Standard) is the analytical standard of m-Iodobenzylguanidine (sulfate). This product is intended for research and analytical applications. m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation).
    m-Iodobenzylguanidine sulfate (Standard)
  • HY-103704R
    LY2562175 (Standard)
    LY2562175 (Standard) is the analytical standard of LY2562175 (HY-103704). This product is intended for research and analytical applications. LY2562175 is a potent and selective FXR agonist, with an EC50 of 193 nM.
    LY2562175 (Standard)
  • HY-103377R
    Antalarmin hydrochloride (Standard)
    Antalarmin (hydrochloride) (Standard) is the analytical standard of Antalarmin (hydrochloride). This product is intended for research and analytical applications. Antalarmin (hydrochloride) is an oral active non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.
    Antalarmin hydrochloride (Standard)
  • HY-101006R
    Methyl 2,5-dihydroxycinnamate (Standard)
    Methyl 2,5-dihydroxycinnamate (Standard) is the analytical standard of Methyl 2,5-dihydroxycinnamate. This product is intended for research and analytical applications. Methyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity.
    Methyl 2,5-dihydroxycinnamate (Standard)
  • HY-101449R
    Adaptaquin (Standard)
    Adaptaquin (Standard) is the analytical standard of Adaptaquin (HY-101449). This product is intended for research and analytical applications. Adaptaquin is a BBB-penetrable HIF-PHDs inhibitor. Adaptaquin has anti-inflammatory and neuroprotective effects. Adaptaquin can effectively inhibit lipid peroxidation, maintain mitochondrial function, and reduce neuronal death. Adaptaquin can be used in the research of nervous system diseases such as Parkinson's disease.
    Adaptaquin (Standard)
  • HY-W002348R
    2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid (Standard)
    2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid (Standard) is the analytical standard of 2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid. This product is intended for research and analytical applications.
    2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid (Standard)
  • HY-34512R
    2,4,5-Trifluorobenzaldehyde (Standard)
    2,4,5-Trifluorobenzaldehyde (Standard) is the analytical standard of 2,4,5-Trifluorobenzaldehyde. This product is intended for research and analytical applications.
    2,4,5-Trifluorobenzaldehyde (Standard)
  • HY-N0719R
    Fargesin (Standard)
    Fargesin (Standard) is the analytical standard of Fargesin. This product is intended for research and analytical applications. Fargesin is a bioactive neolignan isolated from magnolia plants, with antihypertensive and anti-inflammatory effects.
    Fargesin (Standard)
  • HY-102004R
    Rilapladib (Standard)
    Rilapladib (Standard) is the analytical standard of Rilapladib (HY-102004). This product is intended for research and analytical applications. Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM. Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist.
    Rilapladib (Standard)
  • HY-17504BR
    Rosuvastatin Sodium (Standard)
    Rosuvastatin (Sodium) (Standard) is the analytical standard of Rosuvastatin (Sodium). This product is intended for research and analytical applications. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
    Rosuvastatin Sodium (Standard)
  • HY-B1376R
    Methsuximide (Standard)
    Methsuximide (Standard) is the analytical standard of Methsuximide. This product is intended for research and analytical applications. Methsuximide is an anticonvulsant agent. Methsuximide is effective in petit mal, psychomotor and focal motor attacks.
    Methsuximide (Standard)
  • HY-B1953R
    Thiacloprid (Standard)
    Thiacloprid (Standard) is the analytical standard of Thiacloprid. This product is intended for research and analytical applications. Thiacloprid is an orally active neurotoxic insecticide and also a nAChR agonist. Thiacloprid reduces the viability of healthy cells, depletes reduced glutathione, and increases MDA levels, thereby inducing cytotoxicity and oxidative stress damage. In practical applications, Thiacloprid has lower acute toxicity to honeybees than other compounds of the same class such as Imidacloprid (HY-B0838), but it still significantly impairs the learning and memory function, immune capacity and survival status of honeybees. Thiacloprid induces intestinal microbial dysbiosis and reduces survival rate in middle-aged honeybees, increases the risk of premature collapse in bumblebee colonies, and significantly decreases the final colony weight and reproductive output. Thiacloprid is used in broad-spectrum agricultural pest control, often alone or in combination with Deltamethrin (HY-B1971), and meets the pest management needs of various crops including potatoes, cabbages, various fruits and vegetables, and nuts.
    Thiacloprid (Standard)