2. Signaling Pathways
  3. Epigenetics
  4. YTHDF
  5. YTHDF1 Isoform
  6. YTHDF1 Inhibitor

YTHDF1 Inhibitor

YTHDF1 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-176848
    SKLB-Y13
    		Inhibitor 98.44%
    SKLB-Y13 is a selective YTHDF1 inhibitor with an IC50 of 0.76 μM and a KD of 5.097 μM. SKLB-Y13 binds to the Tyr397 and Trp470 residues in the m6A-binding pocket of YTHDF1, disrupting the interaction between YTHDF1 and m6A-modified mRNA. SKLB-Y13 inhibits cancer cell proliferation and promotes apoptosis. SKLB-Y13 is applicable to breast cancer-related research.
  • HY-168610
    YTH-IN-1
    		Inhibitor 98.66%
    YTH-IN-1 (compound N-7) is a pan-YTH domain inhibitor with the IC50 values of 39 μM, 34 μM, 35 μM, 48 μM and 30 μM for human YTHYTHDF1, YTHYTHDF2, YTHYTHDF3, YTHYTHDC1, and YTHYTHDC2, respectively.
  • HY-RS15937
    YTHDF1 Human Pre-designed siRNA Set A
    		Inhibitor

    YTHDF1 Human Pre-designed siRNA Set A contains three designed siRNAs for YTHDF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.