A 131701
A 131701 is a selective α1a- (Ki: 0.22 nM for human α1a) and α1d-adrenoceptor antagonist. A 131701 antagonizes epinephrine-induced increases in intraurethral pressure (IUP). A 131701 causes transient decreases in mean arterial blood pressure (MABP) and transient tachycardia. A 131701 can be used in the research of spontaneous hypertension.
For research use only. We do not sell to patients.
- CAS No.: 181490-18-6
- Formula: C24H24N4O3S
- Molecular Weight:448.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
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α1A-adrenergic receptor 0.22 nM (Ki) |
Alpha-1D adrenergic receptor |
Chemical Information
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CAS No. 181490-18-6
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Molecular Weight 448.54
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Formula C24H24N4O3S
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SMILES
O=C1NC(C2=NC=CC=C2S3)=C3C(N1CCN4C[C@]5([H])CCC6=C(OC)C=CC=C6[C@]5([H])C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A 131701 Related Classifications
HY-135488 Related Classifications
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