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Abrilumab

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Based on 1 Customer Validation

Abrilumab is a fully human monoclonal antibody directed against α4β7. Abrilumab selectively binds the α4β7 integrin heterodimer. Abrilumab can be used for the research of inflammatory bowel disease (IBD).

For research use only. We do not sell to patients.

  • Purity : 98.35%
  • CAS No.: 1342290-43-0
  • Molecular Weight:143.8 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Abrilumab
  • Experimental Validation Results for Abrilumab
  • Experimental Validation Results for Abrilumab
  • Abrilumab Chemical Structure
    Abrilumab Chemical Structure
CAS No.: 1342290-43-0
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Abrilumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All Integrin Isoforms

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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His Tag can bind Abrilumab. The EC50 for this effect is 4.74 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Abrilumab (HY-P99184, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Abrilumab Chemical Structure
    1/16
  • Abrilumab
  • Immobilized Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His Tag can bind Abrilumab. The EC50 for this effect is 4.74 ng/mL.
  • Flow cytometric analysis of 1X106 Jurkat cells with Abrilumab (HY-P99184, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).