AChE/BChE-IN-28
AChE/BChE-IN-28 (Compound 5q) is a BChE inhibitor with an IC50 of 13.49 μM. AChE/BChE-IN-28 also exerts moderate inhibitory effect on AChE, with an IC50 of 35.23 μM. AChE/BChE-IN-28 can be used in the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C22H32N2O5
- Molecular Weight:404.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BChE 13.49 μM (IC50) |
AChE 35.23 μM (IC50) |
Chemical Information
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Molecular Weight 404.50
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Formula C22H32N2O5
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SMILES
O=C(OC(C)(C)C)NC1CN(C(/C=C/C2=CC=C(OCC)C(OC)=C2)=O)CCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/BChE-IN-28 Related Classifications
HY-174464 Related Classifications
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