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Cat. No.: HY-W037850

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Adamantan-2-amine

Name: Adamantan-2-amine
Brand: MedChemExpress
SKU: HY-W037850
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 2-Aminoadamantane)

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Adamantan-2-amine (2-Aminoadamantane) serves as the hydrophobic tag structural unit of Tubulin degrader 2 (HY-161641) and is used for the synthesis of anticancer drugs that target tubulin via a dual mechanism. Adamantan-2-amine can be applied in research on breast cancer, lung cancer, colorectal cancer, and Parkinson's syndrome.

For research use only. We do not sell to patients.

CAS No.: 13074-39-0
Formula: C₁₀H₁₇N
Molecular Weight:151.25

Storage:

RT, protect from light.

In solvent -80°C, 1 year , -20°C, 6 months

Adamantan-2-amine Chemical Structure

CAS No.: 13074-39-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

In Vitro

Adamantan-2-amine (2-Aminoadamantane) (0.05 mol; 20 min) hydrochloride successfully undergoes fusion with dicyandiamide at 190°C to produce 1-(2-adamantyl) biguanide hydrochloride with 85% yield^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 13074-39-0
Appearance Solid
Molecular Weight 151.25
Formula C₁₀H₁₇N
SMILES

NC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Synonyms

2-Aminoadamantane
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, protect from light

In solvent	-80°C	1 year
	-20°C	6 months

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang S, et al. Design, synthesis and biological evaluation of novel tubulin-targeting agents with a dual-mechanism for polymerization inhibition and protein degradation. European journal of medicinal chemistry. 2024 Jun 05;272:116458. [Content Brief]

[2]. Morozov IS, et al. Anticataleptic activity of heterocyclic 2-aminoadamantane derivatives. Pharm Chem J. 2000 Apr;34(4):189-192. doi:10.1007/BF02524595.

[3]. Eisa HM, et al. Synthesis of certain 2-aminoadamantane derivatives as potential antimicrobial agents. Die Pharmazie. 1991 Mar;46(3):182-4.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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