2. PI3K/Akt/mTOR Stem Cell/Wnt Metabolic Enzyme/Protease
  3. GSK-3 Creatine Kinase
  4. AKI-062a

AKI-062a is a non-selective kinase inhibitor, such as a CK1γ inhibitor. AKI-062a binds to and inhibits WNT pathway kinases and GSK3β. At a concentration of 1 μM, AKI-062a binds to 17 kinases, with a binding activity of <10% of that of the control group.

For research use only. We do not sell to patients.

AKI-062a

AKI-062a Chemical Structure

CAS No. : 1093303-07-1

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AKI-062a Related Antibodies

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Description

AKI-062a is a non-selective kinase inhibitor, such as a CK1γ inhibitor. AKI-062a binds to and inhibits WNT pathway kinases and GSK3β. At a concentration of 1 μM, AKI-062a binds to 17 kinases, with a binding activity of <10% of that of the control group[1].

IC50 & Target

GSK-3β

 

In Vitro

AKI-062a (1 μM) demonstrates non-selective kinase binding, interacting with 17 kinases including the WNT pathway kinase GSK3β[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AKI-062a Related Antibodies
Molecular Weight

375.43

Formula

C20H21N7O
CAS No.
SMILES

CN(C)CC(NC1=NNC(C1=C2)=CC=C2C(N=N3)=CN3CC4=CC=CC=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AKI-062a Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKI-062a1093303-07-1GSK-3Creatine KinaseGlycogen synthase kinase-3Glycogen synthase kinase 3CKkinase inhibitorWNT pathway kinasesGSK3βkinasesInhibitorinhibitorinhibit

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