Alentemol hydrobromide
Alentemol (hydrobromide) is a dopamine antagonist and dihydrophenalene analog with dimethylamino substitution and an orthophenolic hydroxy group relative to the amino nitrogen. Alentemol (hydrobromide) does not impair escape response at a dose that completely suppresses conditioned avoidance in rats.
For research use only. We do not sell to patients.
- CAS No.: 112892-81-6
- Formula: C19H26BrNO
- Molecular Weight:364.32
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Dopamine Receptor Isoforms
More
Biological Activity
Alentemol hydrobromide (0.55 mg/kg; intramuscular injection; single dose) blocks apomorphine (HY-12723)-induced vomiting responses in dogs, with an intramuscular ED50 of 0.55 mg/kg[1].
Alentemol hydrobromide (10-30 mg/kg; i.p.; single administration) dose-dependently antagonizes apomorphine-induced stereotyped behaviors in rats[1].
Alentemol hydrobromide (0.03-0.3 mg/kg; intramuscular injection; single administration) blocks the discriminative stimulus effect of Apomorphine in rhesus monkeys, and the Apomorphine-specific lever responses decrease in a dose-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Rhesus monkey with Apomorphine discriminative stimulus[1]
-
Dosage:0.03 mg/kg; 0.1 mg/kg; 0.3 mg/kg
-
Administration:i.m.; single dose; 60 minutes prior to apomorphine challenge
-
Result:Reduced apomorphine-appropriate lever responses in a dose-dependent manner.
Partially reversed the apomorphine-induced reduction in response rate in a dose-dependent manner.
Chemical Information
-
CAS No. 112892-81-6
-
Molecular Weight 364.32
-
Formula C19H26BrNO
-
SMILES
CCCN(C1CC2=C3C(C1)=CC=CC3=CC(O)=C2)CCC.Br
-
Synonyms
U-68553B
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Alentemol hydrobromide Related Classifications
HY-115418 Related Classifications
Powered by Bioz