2. Others
  3. Others
  4. Alphadolone acetate

Alphadolone acetate  (Synonyms: Alfadolone acetate; GR 2/1574)

Cat. No.: HY-108068 Purity: 98.50%
COA Handling Instructions

Molarity Calculator

Alphadolone acetate (Alfadolone acetate) is a steroid anaesthetic, with antinociception.

For research use only. We do not sell to patients.

Alphadolone acetate Chemical Structure

Alphadolone acetate Chemical Structure

CAS No. : 23930-37-2

Size Price Stock Quantity
5 mg USD 115 In-stock
10 mg USD 190 In-stock
25 mg USD 380 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Alphadolone acetate Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Alphadolone acetate (Alfadolone acetate) is a steroid anaesthetic, with antinociception[1].

In Vivo

Alphadolone acetate (anaesthetized with a 3:1 mixture of Alphaxalone and Alphadolone acetate; i.m.) blocks the oestrogen-stimulated luteinizing hormone (LH) surge and impairs pulsatile secretion in female rats, when combined with alphaxalonet[2].
Alphadolone acetate (14 mL/kg; i.p.; single dosage) decreases serum concentrations of LH in castrated rats[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Inbred Wistar-derived colony female rats (intramuscularly injected with 20 µg/100g oestradiol benzoate)[2]
Dosage: Anaesthetized with a 3 :1 mixture of Alphaxalone and Alphadolone acetate
Administration: i.m.
Result: Blocked the oestrogen-stimulated LH surge and impairs pulsatile secretion.
Animal Model: Male Sprague-Dawley rats (orchidectomized; aged 90-120 days and weighing 300-350 g)[3]
Dosage: 14 mL/kg
Administration: i.p.; single dosage
Result: Decreased serum concentrations of LH.
Molecular Weight

390.51

Formula

C23H34O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](O)CC2)([H])[C@@]4([H])[C@@](C)([C@@H](C(COC(C)=O)=O)CC4)CC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (640.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5608 mL 12.8038 mL 25.6075 mL
5 mM 0.5122 mL 2.5608 mL 5.1215 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5608 mL 12.8038 mL 25.6075 mL 64.0188 mL
5 mM 0.5122 mL 2.5608 mL 5.1215 mL 12.8038 mL
10 mM 0.2561 mL 1.2804 mL 2.5608 mL 6.4019 mL
15 mM 0.1707 mL 0.8536 mL 1.7072 mL 4.2679 mL
20 mM 0.1280 mL 0.6402 mL 1.2804 mL 3.2009 mL
25 mM 0.1024 mL 0.5122 mL 1.0243 mL 2.5608 mL
30 mM 0.0854 mL 0.4268 mL 0.8536 mL 2.1340 mL
40 mM 0.0640 mL 0.3201 mL 0.6402 mL 1.6005 mL
50 mM 0.0512 mL 0.2561 mL 0.5122 mL 1.2804 mL
60 mM 0.0427 mL 0.2134 mL 0.4268 mL 1.0670 mL
80 mM 0.0320 mL 0.1600 mL 0.3201 mL 0.8002 mL
100 mM 0.0256 mL 0.1280 mL 0.2561 mL 0.6402 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Alphadolone acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alphadolone23930-37-2Alfadolone GR 2/1574OtherssteroidanaestheticantinociceptionInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Alphadolone acetate
Cat. No.:
HY-108068
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.