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Cat. No.: HY-155409

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ALR-38

ALR-38 is a 5-lipoxygenase (5-LOX) inhibitor (IC₅₀: 1.1 μM) with anti-inflammatory activity. ALR-38 effectively reduces ROS levels in neutrophils.

For research use only. We do not sell to patients.

CAS No.: 241127-61-7
Formula: C₁₉H₁₇NO₄
Molecular Weight:323.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ALR-38 Chemical Structure

CAS No.: 241127-61-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

ALR-38 is a 5-lipoxygenase (5-LOX) inhibitor (IC₅₀: 1.1 μM) with anti-inflammatory activity. ALR-38 effectively reduces ROS levels in neutrophils^[1].

IC₅₀ & Target

5-Lipoxygenase (5-LOX)^[1]

All Lipoxygenase Isoforms :

Chemical Information

CAS No. 241127-61-7
Molecular Weight 323.34
Formula C₁₉H₁₇NO₄
SMILES

O=C(C1=CC=C(NCC2=C(O)C3=C(C=CC=C3)C(O)=C2)C=C1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cerchia C et al. Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screening. Eur J Med Chem. 2023 Nov 8;263:115932. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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