1. GPCR/G Protein
  2. Free Fatty Acid Receptor
  3. AM-4668

AM-4668 

Cat. No.: HY-12585 Purity: ≥99.0%
COA Handling Instructions

AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively.

For research use only. We do not sell to patients.

AM-4668 Chemical Structure

AM-4668 Chemical Structure

CAS No. : 1011531-27-3

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Description

AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1].

IC50 & Target

EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1]

Molecular Weight

488.48

Formula

C24H19F3N2O4S

CAS No.
SMILES

OC(C[[email protected]](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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AM-4668
Cat. No.:
HY-12585
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