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Anticancer agent 103 (Compound 2k) is a potent anticancer agent.

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Anticancer agent 103 Chemical Structure

Anticancer agent 103 Chemical Structure

CAS No. : 2914922-78-2

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Anticancer agent 103 Related Antibodies

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Description

Anticancer agent 103 (Compound 2k) is a potent anticancer agent[1].

In Vitro

Anticancer agent 103 (Compound 2k; 12.5-400 μM; 24 or 48 h) inhibits HepG2 cell viability, but not Colo-205 viability[1].
Anticancer agent 103 (25 and 50 μM; 24 h) increases the FoXO1, TXNIP and p27 protein levels in HepG2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 103 Related Antibodies

Cell Viability Assay[1]

Cell Line: HepG2 and Colo-205 cells
Concentration: 12.5, 25, 50, 100, 200 and 400 μM
Incubation Time: 24 or 48 h
Result: Demonstrated anticancer activity against cancer cell line HepG2 with IC50s of 30.5 μM and 14.8 μM for 24h and 48 h, respectively. The IC50 for Colo-205 was >400 μM.

Western Blot Analysis[1]

Cell Line: HepG2 cells
Concentration: 25 and 50 μM
Incubation Time: 24 h
Result: Increased the FoXO1, TXNIP and p27 protein levels.
Molecular Weight

374.27

Formula

C18H20BrN3O
CAS No.
SMILES

O=C(C1=CC=C(NCCCC)C=C1)N/N=C/C2=CC=C(C=C2)Br
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Anticancer agent 103 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 1032914922-78-2Anticancer agent103Anticancer agent-103OthersHepG2Colo-205FoXO1TXNIPp27Inhibitorinhibitorinhibit

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