Anticancer agent 103
Anticancer agent 103 (Compound 2k) is a potent anticancer agent.
For research use only. We do not sell to patients.
- CAS No.: 2914922-78-2
- Formula: C18H20BrN3O
- Molecular Weight:374.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Anticancer agent 103 (Compound 2k; 12.5-400 μM; 24 or 48 h) inhibits HepG2 cell viability, but not Colo-205 viability[1].
Anticancer agent 103 (25 and 50 μM; 24 h) increases the FoXO1, TXNIP and p27 protein levels in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HepG2 and Colo-205 cells
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Concentration:12.5, 25, 50, 100, 200 and 400 μM
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Incubation Time:24 or 48 h
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Result:Demonstrated anticancer activity against cancer cell line HepG2 with IC50s of 30.5 μM and 14.8 μM for 24h and 48 h, respectively. The IC50 for Colo-205 was >400 μM.
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Cell Line:HepG2 cells
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Concentration:25 and 50 μM
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Incubation Time:24 h
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Result:Increased the FoXO1, TXNIP and p27 protein levels.
Chemical Information
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CAS No. 2914922-78-2
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Molecular Weight 374.27
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Formula C18H20BrN3O
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SMILES
O=C(C1=CC=C(NCCCC)C=C1)N/N=C/C2=CC=C(C=C2)Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 103 Related Classifications
HY-149216 Related Classifications
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