2. MAPK/ERK Pathway Stem Cell/Wnt
  3. ERK
  4. Anticancer agent 301

Anticancer agent 301 is an anticancer agent. Anticancer agent 301 selectively downregulates the phosphorylation level of ERK1/2 without affecting the NF-κB p65 subunit. Anticancer agent 301 exhibits antiproliferative activity against breast cancer cells and can be used in breast cancer-related research.

For research use only. We do not sell to patients.

Anticancer agent 301

Anticancer agent 301 Chemical Structure

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Anticancer agent 301 Related Antibodies

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Description

Anticancer agent 301 is an anticancer agent. Anticancer agent 301 selectively downregulates the phosphorylation level of ERK1/2 without affecting the NF-κB p65 subunit. Anticancer agent 301 exhibits antiproliferative activity against breast cancer cells and can be used in breast cancer-related research[1].

IC50 & Target[1]

ERK1

 

ERK2

 

In Vitro

Anticancer agent 301 potently inhibits proliferation of MCF-7 human breast cancer cells with an IC50 of 15.34 ± 0.17 μM[1].
Anticancer agent 301 (12.5-100 μM) selectively inhibits ERK1/2 phosphorylation in MCF-7 human breast cancer cells at 25 μM, without affecting NF-κB p65 phosphorylation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 301 Related Antibodies
Molecular Weight

318.37

Formula

C20H18N2O2
SMILES

O=C(N1CCC2=C(NC3=CC=CC=C32)C1)/C=C/C4=CC=C(C=C4)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anticancer agent 301 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 301Anticancer agent301Anticancer agent-301ERKExtracellular signal regulated kinasesMCF-7 human breast cancer cellsERK2NF-κB p65 subunitbreast cancer cellsERK1ERK1/2 kinase domainstetrahydro-β-carboline scaffoldERK1/2Inhibitorinhibitorinhibit

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