Antifungal agent 137
Antifungal agent 137 (Compound 4S) is an antifungal agent. Antifungal agent 137 inhibits Phomopsis sp. (PS), with an EC50 of 0.15 μg/mL. Antifungal agent 137 inhibits lanosterol 14α-demethylase (CYP51), with an IC50 of 5.00 μg/mL. Antifungal agent 137 disrupts the morphology of PS mycelia, impairs cell membrane integrity, and induces an increase in intracellular ROS levels, triggering oxidative stress. Antifungal agent 137 can be used for the study of fungal infection.
For research use only. We do not sell to patients.
- CAS No.: 3032062-22-6
- Formula: C21H21F4N5O3S
- Molecular Weight:499.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CYP51 5.00 μg/mL (IC50) |
Chemical Information
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CAS No. 3032062-22-6
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Molecular Weight 499.48
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Formula C21H21F4N5O3S
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SMILES
OC(CN1N=CN=C1)(C2=CC=C(F)C=C2F)CN3CCN(S(=O)(C4=CC(F)=CC=C4F)=O)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 137 Related Classifications
HY-178340 Related Classifications
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