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  4. Antileishmanial agent-14

Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM).

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Antileishmanial agent-14 Chemical Structure

Antileishmanial agent-14 Chemical Structure

CAS No. : 1638956-72-5

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Antileishmanial agent-14 Related Antibodies

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Description

Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM)[1].

In Vitro

Antileishmanial agent-14 (compound 2o) (25 μM, 50 μM) inhibits activity of L. donovani amastigotes with inhibitory rates of 116% and 115% at 25 μM and 50 μM, respectively[1].
Antileishmanial agent-14 decreases L. donovani amastigotes parasite number with IC50 of 4.6 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antileishmanial agent-14 Related Antibodies
Molecular Weight

431.91

Formula

C23H26ClNO5
CAS No.
SMILES

O=C1C2=CC=C(OCCN3CCCC3)C=C2O/C1=C\C4=C(C=CC(OC)=C4)OC.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antileishmanial agent-14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antileishmanial agent-141638956-72-5Antileishmanial agent14Antileishmanial agent 14ParasiteLeishmania donovani promastigotesL. donovani amastigotessulfuretin analogInhibitorinhibitorinhibit

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