Antileishmanial agent-14
Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM).
For research use only. We do not sell to patients.
- CAS No.: 1638956-72-5
- Formula: C23H26ClNO5
- Molecular Weight:431.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | CC50 |
10.5 μM
Compound: 2o
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Cytotoxicity against human THP-1 cells
Cytotoxicity against human THP-1 cells
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[PMID: 36944273] |
Antileishmanial agent-14 (compound 2o) (25 μM, 50 μM) inhibits activity of L. donovani amastigotes with inhibitory rates of 116% and 115% at 25 μM and 50 μM, respectively[1].
Antileishmanial agent-14 decreases L. donovani amastigotes parasite number with IC50 of 4.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1638956-72-5
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Molecular Weight 431.91
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Formula C23H26ClNO5
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SMILES
O=C1C2=CC=C(OCCN3CCCC3)C=C2O/C1=C\C4=C(C=CC(OC)=C4)OC.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antileishmanial agent-14 Related Classifications
HY-149093 Related Classifications
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