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Cat. No.: HY-149834

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Antileishmanial agent-18

Antileishmanial agent-18 (Compound 1e) is an antileishmanial agent. Antileishmanial agent-18 effectively inhibits growth of L. donovani promastigotes. Antileishmanial agent-18 is safe for host cells.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1007567-02-3
화학식: C₂₈H₂₇N₃O₄
분자량:469.53

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antileishmanial agent-18 Chemical Structure

CAS No.: 1007567-02-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK-293T	CC₅₀	>200 μM Compound: 1e	Cytotoxicity against human HEK293T cells assessed as cell death by measuring metabolism of resazurin to resorufin measured after 3 days Cytotoxicity against human HEK293T cells assessed as cell death by measuring metabolism of resazurin to resorufin measured after 3 days	[PMID: 36827952]
THP-1	CC₅₀	93 μM Compound: 1e	Cytotoxicity against human THP-1 cells assessed as cell death by measuring metabolism of resazurin to resorufin measured after 3 days Cytotoxicity against human THP-1 cells assessed as cell death by measuring metabolism of resazurin to resorufin measured after 3 days	[PMID: 36827952]

Chemical Information

CAS No. 1007567-02-3
분자량 469.53
화학식 C₂₈H₂₇N₃O₄
SMILES

CC1=C(NC2=CC=CC=C2C1=O)C(N[C@H]([C@H](C(NCC3=CC=CC=C3)=O)O)CC4=CC=CC=C4)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hassan AHE, et al. Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies. Eur J Med Chem. 2023 Mar 15;250:115211. [Content Brief]

[2]. Hassan AHE, et, al. Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies. Eur J Med Chem. 2023 Mar 15;250:115211. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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